“The function of neuroglia in Health and Disease - Dialogue between glia and neurons”, Series: Advances in Experimental Medicine and Biology. A scientific book of approximately 400 pages covering recent advances in glial cell biology and pathology, Plenum Press, 1999, edited by R. Matsas and M. Tsacopoulos.

· Matsas R., Proud D., Nustad K. and Bailey G.S. (1981). Rapid purification of a prekallikrein from rat pancreas. Anal.Biochem.113:264-270.

· Yussof K.M., Proud D., Matsas R. and Bailey G.S. (1981). The existence of a trypsin inhibitor-prekallikrein complex in rat pancreatic homogenates. Biochem. Int. 2:211-217.

· Fulcher I.S., Matsas R., Turner A.J. and Kenny A.J. (1982). Kidney endopeptidase and the hydrolysis of enkephalin by synaptic membranes show similar sensitivity to inhibitors. Biochem.J. 203:519-522.

· Matsas R., Fulcher I.S., Kenny A.J. and Turner A.J. (1983). Substance P and [Leu]enkephalin are hydrolysed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli. Proc. Natl. Acad. Sci. U.S.A. 80:3111-3115.

· Matsas R., Fulcher I.S., Kenny A.J. and Turner A.J. (1983). The role of neutral endopeptidase in neuropeptide metabolism. Biochem. Soc. Trans. 11:372-373.

· Gee N.S., Matsas R. and Kenny A.J. (1983). A monoclonal antibody to kidney endopeptidase-24.11. Its application in immunoadsorbent purification of the enzyme and immunofluorescence microscopy of kidney and intestine. Biochem. J. 214:377-386.

· Relton J.M., Gee N.S., Matsas R., Turner A.J. and Kenny A.J. (1983). Purification of endopeptidase-24.11 (“enkephalinase”) from pig brain by immunoadsorbent chromatography. Biochem. J. 215:519-440.

· Matsas R., Kenny A.J. and Turner A.J. (1984). The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase 24.11. Biochem. J. 223:433-440.

· Matsas R., Turner A.J. and Kenny A.J. (1984). Endopeptidase-24.11 and aminopeptidase activity in brain synaptic membranes are jointly responsible for the hydrolysis of cholecystokinin octapeptide (CCK-8). FEBS Lett. 175:124-128.

· Kenny A.J., Matsas R. and Turner A.J. (1984). Structure, distribution and function of endopeptidase-24.11. In: Regulation of Transmitter Function: Basic and Clinical Aspects (E.S. Vizi and K. Magyar, eds.), Elsevier, pp. 257-264.

· Kenny A.J., Gee N.S., Matsas R., Stewart J., Bowes M. and Turner A.J. (1985). Endopeptidase-24.11: A general purpose membrane enzyme for metabolising peptides. Prog. Clin. Biol. Res. 180:175-184.

· Matsas R., Kenny A.J. and Turner A.J. (1985). Endopeptidase-24.11 “enkephalinase”: Its role in the central nervous system. Prog. Clin. Biol. Res. 180:273-277.

· Turner A.J., Matsas R. and Kenny A.J. (1985). Endopeptidase-24.11 and neuropeptide metabolism. Biochem. Soc. Trans. 13:39-42.

· Kenny A.J., Bowes M.A., Gee N.S. and Matsas R. (1985). Endopeptidase-24.11: a cell-surface enzyme for metabolizing regulatory peptides. Biochem. Soc. Trans. 13:293-295.

· Turner A.J., Matsas R. and Kenny A.J. (1985). Are there neuropeptide-specific peptidases? Biochem. Pharmacol. 34:1347-1356.

· Matsas R., Rattray M., Kenny A.J. and Turner A.J. (1985). The metabolism of neuropeptides. Endopeptidase-24.11 in human synaptic membrane preparations hydrolyses substance P. Biochem. J. 228:487-492.

· Matsas R., Stephenson S.L., Hryszko J., Kenny A.J. and Turner A.J. (1985). The metabolism of neuropeptides. Phase separation of synaptic membrane preparations with Triton X-114 reveals the presence of aminopeptidase N. Biochem. J. 231:445-446.

· Matsas R., Kenny A.J. and Turner A.J. (1985). Immunocytochemical localization of endopeptidase-24.11 in the pig brain. Biochem. Soc. Trans. 13:354-356.

· Turner A.J., Matsas R. and Kenny A.J. (1986). Metabolism of Cholecytokinin by endopeptidase-24.11. Annals New York Acad. Sci. 448:666-668.

· Matsas R., Turner A.J. and Kenny A.J. (1986). An immunocytochemical study of endopeptidase-24.11 (enkephalinase) in the pig nervous system. Neuroscience 18:991-1012.

· Turner A.J., Kenny A.J. and Matsas R. (1986). Endopeptidases: aspects of enzymology must be considered. Trends Pharmacol. Sci.88-89.

· Matsas R., Kenny A.J. and Turner .J. (1987). Localization of endopeptidase-24.11 in the nervous system. Synaptic transmitters and Receptors (ed Tucek S), John Wiley, pp. 205-209.

· Barnes K., Matsas R., Hooper N.M., Turner A.J. and Kenny A.J. (1988). Endopeptidase-24.11 is striosomally ordered in pig brain and in contrast to aminopeptidase N and peptidyl dipeptidase A (“angiotensin converting enzyme”) is a marker for a set of striatal efferent fibres. Neuroscience 27:799-817.

· Patsavoudi E., Hurel C. and Matsas R. (1989). Neuron and myelin-specific monoclonal antibodies recognizing cell-surface antigens of the central and peripheral nervous system. Neuroscience 30:463-478.

· Matsas R. and Kenny A.J. (1989) Immunocytochemical localization of endopeptidase-24.11 in cultured neurons from pig striatum. Neuroscience 31:237-246.

· Patsavoudi E., Hurel C. and Matsas R. (1991). Purification and characterization of neuron specific surface antigen defined by monoclonal antibody BM88. J .Neurochem. 56:782-788.

· Kioussi C. and Matsas R. (1991). Endopeptidase-24.11 a cell surface peptidase of CNS neurons, is expressed by Schwann cells in the pig PNS. J. Neurochem. 57:431-440.

· Merkouri E. and Matsas R. (1992). Monoclonal antibody BM89 recognizes a novel cell surface glycoprotein of the L2/HNK-1 family in the developing mammalian nervous system. Neuroscience 50:53-68.

· Kioussi C., Crine P. and Matsas R. (1992). Endopeptidase-24.11 is suppressed in myelin-forming but not in non-myelin-forming Schwann cells during development of the rat sciatic nerve. Neuroscience 50:69-83.

· D. Thomaidou and E. Patsavoudi (1993). “Monoclonal antibody 4C5 recognizes a novel neuron specific antigen in the developing nervous system” Neuroscience 53: 813-827.

· Patsavoudi E., Merkouri E., Thomaidou D., Sandillon F., Alonso G. and Matsas R. (1995). Characterization and localization of the BM88 antigen in the developing and adult rat brain. J. Neurosci. Res. 40:506-518

· Kioussi C., Mamalaki A., Jessen K. R., Mirsky R., Hersh L. B. and Matsas R. (1995). Expression of endopeptidase-24.11/ common acute lymphoblastic leukemia antigen CD10 in the sciatic nerve of the adult rat after lesion and during regeneration. Eur. J. Neurosci.7:951-961.

· Mamalaki A., Boutou E., Hurel C., Patsavoudi E., Tzartos S. and Matsas R. (1995). The BM88 antigen, a novel neuron-specific molecule, promotes the differentiation of mouse neuroblastoma cells. J. Biol. Chem. 270:14201-14208.

· J. G. Parnavelas, M. C. Mione and A. A. Lavdas (1995) The cell lineage of neuronal subtypes in the mammalian cerebral cortex Ciba Found Symp.193:41-58.

· D. Thomaidou, I. Dori and E. Patsavoudi (1995). “Developmental expression and functional characterization of the 4C5 antigen in the postanatal rat cerebellar cortex” J. Neurochem. 64: 1937-1944.

· Soteriadou K. P., Tzinia A. K., Panou-Pomonis E., Tsikaris V., Sakarellos-Daitsiotis M., Sakarellos C., Papapoulou Y. and Matsas R. (1996). Antigenicity and conformational analysis of the zinc-binding sites of two zinc-metalloproteases: Leishmania gp63 and mammalian endopeptidase-24.11. Biochem. J. 313:455-466.

· Lavdas AA, M. C. Mione and J. G. Parnavelas (1996) Neuronal clones in the cerebral cortex show morphological and neurotransmitter heterogeneity during development. Cerebral Cortex, 6: 490-497.

· Lineage analysis of neurons by means of beta-galactosidase labelling. M. C. Mione, I. S. Pappas, A. A. Lavdas and J. G. Parnavelas (1996) Neuroscience Protocols, 96-030-01, 1-15.

· D.Thomaidou, E. Yfanti and E. Patsavoudi (1996). “Expression of the 4C5 antigen in the rat sciatic nerve during development and after regeneration” J. Neurosci. Res. 40: 506-518.

· Matsas R. and Meintanis S. (1997). Endopeptidase-24.11/common acute lymphoblastic leukemia antigen CD10 in Schwann cells: evidence for a role in nerve development and regeneration. In: “Molecular signaling and regulation in glial cells: a key to remyelination and functional repair”, G. Jeserich, H. H. Althaus, C. Richter-Landsberg and R. Heumann, eds., Springer Verlag, Heidelberg, pp. 28-43.

· Gaitanou M., Mamalaki A., Merkouri E. and Matsas R. (1997) Purification and cDNA cloning of the mouse BM89 antigen shows that it is identical with the synaptic vesicle protein synaptophysin. J. Neurosci. Res., 48:507-514.

· Matsas R. (1997). Genes controlling neural fate and differentiation Adv. Exp. Med. Biol. 429:3-17.

· Lavdas AA, M. E. Blue, J. Lincoln and J. G. Parnavelas (1997) Serotonin promotes the differentiation of glutamate neurons in organotypic slice cultures of the developing cerebral cortex. J. Neurosci., 17: 7872-7880.

· D. Thomaidou, M. C. Mione, J. F. R. Cavanagh and J. G. Parnavelas (1997). “Apoptosis and its relation to the cell cycle in the developing cerebral cortex.” J. Neurosci. 17(3): 1075-1085.

· B. Nadarajah, D. Thomaidou , W. H. Evans and J. G. Parnavelas (1997). “Gap junctions in the adult cerebral cortex: regional differencies in their distribution and cellular expression of connexins” J. Comp. Neurol. 376: 326-342.

· Gomez J., Boutou E., Hurel C., Mamalaki A., Kentroti S., Vernadakis A. and Matsas R. (1998). Overexpression of the neuron-specific molecule BM88 in mouse neuroblastoma cells: altered responssiveness to growth factors. J. Neurosci. Res., 51:119-128.

· Kozlov IA, Politis PK, Van Aerschot A, Busson R, Herdewijn P, Orgel LE. (1999) Nonenzymatic synthesis of RNA and DNA oligomers on hexitol nucleic acid templates: the importance of the A structure. J Am Chem Soc. 121:2653-6.

· Kozlov IA, Politis PK, Pitsch S, Herdewijn P, Orgel LE (1999) A highly enantio-selective hexitol nucleic acid template for nonenzymatic oligoguanylate synthesis. J Am Chem Soc.;121:1108-9.

· Lavdas AA, M. Grigoriou, V.Pachnis and J.G.Parnavelas (1999) Τhe medial ganglionic eminence gives rise to a population of early neurons in the developing cerebral cortex. J. Neurosci., 19: 7881-7888.

· B. Naqui, S. Harris, D. Thomaidou and J.G. Parnavelas (1999). “The noradrenergic system influences the pattern of development of Cajal-Retzius cells in the cerebral cortex” Brain Res. Dev Brain Res. 113(1-2): 75-82.

· Boutou E., Hurel C., Mamalaki A. and Matsas R. (2000). Early expression of the BM88 antigen in differentiating P19 embryonal carcinoma cells. Int. J. Dev. Neurosci., Special Issue: Multiple mechanisms in brain maturation and degeneration,18:321-328.

· Parnavelas JG, Anderson SA, Lavdas AA, Grigoriou M, Pachnis V, Rubenstein JL. (2000) The contribution of the ganglionic eminence to the neuronal cell types of the cerebral cortex. Novartis Found Symp. 228:129-39.

· Boutou E., R. Matsas and A. Mamalaki. (2001) Isolation of a mouse brain cDNA expressed in developing neuroblasts and mature neurons. Brain Res. Mol. Brain Res., 86:153-167.

· Meintanis S., Jessen K.R., Mirsky R. and Matsas R. (2001). The Neuron-Glia Signal β-Neuregulin Promotes Schwann Cell Motility via the MAPK Pathway. GLIA 34:39-51.

· Gaitanou M., Buanne P., Pappa C., Georgopoulou N., Mamalaki A., Tirone F. and Matsas R. (2001). Cloning, expression and localization of human BM88 shows that it maps to chromosome 11p15.5, a region implicated in Beckwith-Wiedemann syndrome and tumorigenesis. Biochem. J., 355:715-724.

· Katsetos CD, Del Valle L, Geddes JF, Assimakopoulou M, Legido A, Boyd JC, Balin BJ, Parikh NA, de Chadarevian J-P, Maraziotis T, Varakis JN, Matsas R, Spano A, Frankfurter A, Herman MM, Khalili K. (2001) Aberrant localization of the neuronal class III beta-tubulin in astrocytomas: A marker for anaplastic potential. Archives of Pathology and Laboratory Medicine (Official publication of the College of American Pathologists), 125:613–624.

· D. Thomaidou, D. Coquillat, S. Meintanis, M. Noda, G. Rougon and R. Matsas. (2001). NCAM and F3 neural cell adhesion molecules promote Schwann cell migration: identification of protein tyrosine phosphatases ζ/β as the putative F3 receptors on Schwann cells, J. Neurochem., 78:767-78.

· Kent NA, Karabetsou N, Politis PK, Mellor J. (2001) In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p. Genes Dev. 15:619-26.

· C.-H. Chan, L.N. Godinho, D. Thomaidou, S.-S. Tan, M. Gulisano and J.G. Parnavelas (2001). “Emx1 is expressed in pyramidal neurons of the cerebral cortex” Cerebral Cortex 11: 1191-1198

· Gravvanis A., Karvelas M., Lykoudis E., Lavdas A.A, Papalois A., Petralexis C., Matsas R., Stamatopoulos C., Ioannovich J. (2003). The use of slicone tubes in end-to-side nerve grafting: an experimental study. Eur. J. Plast. Surg. 26:111-115.

· Meintanis S., Jessen K.R., Mirsky R. and Matsas R. (2004). EDTA is a potent inhibitor of myelination in vivo during development of the rat sciatic nerve, GLIA 48:132-44.

· Koutmani Y, Hurel C, Patsavoudi E, Hack M, Gotz M, Thomaidou D and Matsas R. (2004) BM88 is a marker of proliferating cells that will differentiate into the neuronal lineage, Eur.J.Neurosci. 20:2509-23.

· Martinez-Campa C, Politis P, Moreau JL, Kent N, Goodall J, Mellor J, Goding CR. (2004) Precise nucleosome positioning and the TATA box dictate requirements for the histone H4 tail and the bromodomain factor Bdf1. Mol Cell. 15:69-81.

· Gravvanis A., Lavdas A.A, Francheschini I., Papalois A., Dubois-Dalcq M., Matsas R., Ioannovich J. (2005) The effect of genetically modified Schwann cells to end-to-side nerve grafting Microsurgery, in press.

· Gravvanis A., Lavdas A.A, Papalois A., Tsoutsos DA, Panayotou PN, Francheschini I., Dubois-Dalcq M. and Matsas R., (2005) Collagen tube lined with genetically modified Schwann cells with increased motility : a new promising bioartificial nerve graft. European Journal of Surgery, in press.

· Papadodima O, Sergaki M, Hurel C, Mamalaki A. and Matsas R. (2005) Characterization of the BM88 promoter and identification of an 88 bp fragment sufficient to drive neuron-specific expression, J. Neurochem., accepted for publication.

· Politis P., Geissen M., Rohrer H. and Matsas R. (2005) bm88/cexid is a cell intrinsic determinant that coordinates cell cycle exit and differentiation of neuronal precursors, submitted.

· Lavdas A. Franceschini IA, Papastefanaki F, Dubois-Dalcq M and Matsas R. (2005) Schwann cells genetically engineered to express PSA show enhanced migratory potential without impairment of their myelinating ability, submitted.