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General Services
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| Dept. of Animal Models for Biomedical Research |
Department page | Research & Development
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Head of Laboratory: Lesley Probert, Ph.D., lesley_probert@hol.gr,
Tel: +30-210-64 78 866/863; Fax: +30-210-64 56 547 |
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- Breeding - Distribution Unit
- Vaccine - Quality control Unit
- Histopathology Unit
- Large rodent Unit
- Quarantine
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Specifically qualified staff assists researchers with individual work plans to address project-specific requirements and consult on important colony decisions such as health and welfare of the animals in our care, as well as ways to overcome breeding or phenotype complexities as they arise
Services:
▫ Provide inbred, outbred, transgenic, mutant, and gene targeted mice (many of which are in-house mice), rats, and guinea pigs- low cost – high quality
▫ Colony maintenance and development
▫ Manipulation of immunodeficient/immunocompetent mice
▫ Quarantine and health monitoring
▫ Genotyping and characterization of transgenic mice
▫ Embryo and sperm bank (in progress)
▫ Rederivation (embryo transfer) speed colonies
▫ Congenic strains
▫ Drug/agent administration by different routes: iv, ip, sc, per os
▫ Blood sampling, sera collection, tissue collection
▫ Provide frozen and paraffin embedded tissues from
▫ any animal model requested
▫ Microscopic evaluation of tissue pathologies
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▫ Polyclonal Ab production
▫ Toxicity tests
▫ Vaccine quality control
Order forms >>
- Breeding- Distribution Unit
Specific pathogen free conditions, SPF
Resonsible: Dr Anna Marandidou, Veterinarian tel:+30 210 64 78 800
Animal caretaker: Dimitris Dimos, Nikos Vlachoyiannis
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List 1
Mouse resources:
▫ Inbred mice
▫ Outbred mice
▫ Mutant and gene targeted mouse strains
▫ (many of them are our research products-in house)
Rat resourses
3 strains: Lewis NHSd, Wistar Hsd Han and Sprauge Dawley
Guinea Pigs
Distributed for quality control
- Vaccine-Quality control Unit
Specific pathogen free conditions, SPF
Responsible: Dr D. Sofianos, Biologist-Chemist, Research Engineer A
Laboratory of Quality Control, e mail:sofianos@pasteur.gr Τηλ. +30 210 6478829
Staff:Dr G. Kikis, Veterinarian, Τel. +30 210 6478831
Animal caretaker: Th. Vanakas
Guinea pigs area
quality control testing of vaccines produced by the Vaccine Unit
Mice area
Toxicology tests for diagnostic purposes
Conventional conditions, CV)
Responsible: Dr L. Probert, Biologist, Researcher Α
Dr. S Haralambous, Biologist, Researcher B
Lab of Molecular genetics |  |
Tissue collection, embedding, sectioning, slide preparation, staining and microscopic evaluation
Leica EG1120 microtome Leica RM 2135, Medite tissue floatation bath TFB35,
Leica CH1900
Conventional conditions, CV
Responsible: Dr Anna Marandidou, Veterinarian tel:+30 210 64 78 800
Husbandry: Th. Vanakas, τηλ. 210 6478800 εσωτ. 895
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Housing capacity:
30 individually caged rabbits
▫ Production of polyclonal antibodies
▫ Other experimental protocolsli
Conventional conditions
Responsible: Dr Anna Marandidou, Veterinarian tel:+30 210 64 78 800
Animal caretaker: Th. Vanakas, τηλ. 210 6478800 εσωτ. 895
▫ Transient Housing of animals from other facilities maximum for one month.
▫ The animals for the SPF are scheduled for egg transfer (rederivation)
Housing capacity: About 200 mice
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