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HPI seminars 2008 - 2009    06/02/2009



Hellenic Republic
Ministry of Development
General Secretariat
for Research and Technology
 
127, Vas. Sofias Avenue 11521,
Athens, Greece 
Τel: (+30) 210 6478 800
 Fax: (+30) 210 6423 498
 
 
 
Publications
 

:: Laboratory :: Μembers :: Research Programs :: Funding ::


Publications (1998-2005):

 

A.Varaklioti., U.Georgopoulou., A.Kakkanas, L. Psaridi, W. Caselmann, P.Mavromara (1998). Mutational analysis of two unstructured domains of the 5’UTR of HCV RNA. Biochem Biophys Res Commun 253:678-685
 
Psaridi, L., Georgopoulou, U., Varaklioti, A., Mavromara, P (1999). Mutational analysis of a conserved tetraloop in the 5’ untranslated region of hepatitis C virus identifies a novel RNA element essential for the internal ribosome entry site function. FEBS Lett 453: 49-53
 
Miriagou, V., Stevanato, L., Manservigi, P., Mavromara, P (2000). The C-terminal cytoplasmic tail of herpes simplex virus type 1 gE protein is phosphorylated in vivo and in vitro by cellular enzymes in the absence of other viral proteins J Gen Virol. 81: 1027-1031
 
Κalliampakou K, Psaridi-Linardaki L., Mavromara P (2002). Mutational analysis of the apical region of domain II of the HCV IRES. FEBS Lett. 30;511(1-3): 79-84
 
Varaklioti A., Vassilaki N., Georgopoulou U. Mavromara P. (2002). Alternate translation occurs within the core coding region of the hepatitis C viral genome. J Biol Chem 277:17713-17721
 
Kalamvoki M., Miriagou V., Hadziyannis A., Georgopoulou U., Varaklioti R., Hadziyannis S., and Mavromara P (2002). Expression of immunoreactive forms of the hepatitis C NS5A protein in E.coli and their use for diagnostic assays. Arch Virol 147 (9):1733-1745
 
E. Tsitoura, M. Lucas, V. Revol-Guyot, Al. Epstein, R. Manservigi and P. Mavromara (2002). Expression of hepatitis C virus envelope glycoproteins by herpes simplex virus type 1-based amplicon vectors. J Gen Virol 83: 561-566
 
U. Georgopoulou, K. Caravokiri and P. Mavromara (2003). Suppression of the ERK1/2 signaling pathway from HCV NS5A protein expressed by herpes simplex recombinant viruses. Arch Virol  148(2):237-251
 
M. Lucas, E. Tsitoura, M. Montoya, B. Laliotou, E. Aslanoglou, C. Entwisle, J. Miller, P. Klenerman, A. Hadziyannis, S. Hadziyannis, P. Borrow and P. Mavromara (2003). Characterisation of secreted and intracellular forms of a truncated HCV E2 protein expressed by a recombinant herpes simplex virus J Gen Virol 84(Pt3):545-554
 
N. Vassilaki and P. Mavromara (2003). Two alternative mechanisms are responsible for the synthesis of HCV ARFP/F/core+1 J Biol Chem 278 (42): 40503-40513
 
Lauterbach H, Berto E, Kerksiek K, Busch D, Berto E, Bozac A, Mavromara P, Manservigi R, Epstein AL, Marconi P and Brocker T (2004). Protection from Bacterial infection by a single vaccination with replication-deficient mutant herpes simplex virus-1 J Virol 78: 4020-4028
 
M Kalamvoki and P. Mavromara (2004). Calcium - dependent calpain proteases are implicated in processing of the hepatitis C NS5A protein J Virol 78 (21): 11865-11878

R. Manservigi, A. Boero, R. Argnani, S. Zucchini, V. Miriagou, P. Mavromara, M. Cilli, E. Caselli, M. Grossi, P. Balboni, E. Cassai (2005). Immunotherapeutic activity of a recombinant combined gB-gD-gE vaccine against recurrent HSV-2 infections in a guinea pig model Vaccine 23 (7): 865-872
 
K. Kalliampakou, M. Kalamvoki and P. Mavromara (2005). The HCV NS5A protein down-regulates the HCV IRES-dependent translation J Gen Virol 86 (Pt 4): 1015-25

U. Georgopoulou, P. Tsitoura, M. Kalamvoki and P. Mavromara (2005). The phosphatase 2A represents a novel cellural target for Hepatitis C NS5A protein J Gen VIrol (submitted)


Patents:
 

Mavromara et al «Compositions and Methods for the identification of viral inhibitors of host cell protein synthesis shut-off». Pending Patent Application
 
Mavromara P., Varaklioti A., Georgopoulou O. «Nucleic acids and new polypeptides  associated with and/or overlapping with HCV core gene products» USA Patent  Granted.
 
Mavromara P. Vassilaki N “Novel HCV core+1 protein, methods for diagnosis of HCV infections, prophylaxis and for screening of anti-HCV agents” Pending Patent Application
 
G Janvier, J Decalf, P Mavromara, Y Riviere, S. Pol “Immunogenic peptides  derived from HCV core+1 protein of HCV, comprising T epitopes” Pending Patent Application 

 
 
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