|“There is no type of science that can be qualified as ‘applied science.’ There is only Science and its scientific applications related as the fruit is to the tree that bears it ”|
~ Louis Pasteur
HPI has currently a strong record and international recognition for its basic and translational research in the fields of Infectiology, Immunology and Neuroscience- Neuroimmunology. A unique feature that distinguishes HPI from the other National Research Centres in Greece is its strong commitment to bridge research activities with their applications to Public Health and its participation in an International Network of 32 Pasteur Institutes devoted to the fight of Infectious Diseases.
Research in Infectiology is focused on a selected number of significant pathogens with high socio-economic impact on a National and European level, including hepatitis C virus (HCV), protozoa Leishmania and Trypanosoma brucei (T. brucei), gram-negative bacteria such as enterobacteria, non-fermentive bacilli, Neissseria gonorrhoeae, Helicobacter pylori and Chlamydia.
Studies in Immunology aim to better understand basic mechanisms of innate and adaptive immunity and of immune-mediated disease pathogenesis. During the last few years research have led to the development of immunodiagnostics, therapeutic reagents for cancer and autoimmune diseases and transgenic and mutant mouse models for human diseases.
The Neuroscience and Neuroimmunology Laboratories of HPI are focused on the study of neuromuscular function and neuroimmune interactions, stem cell biology and directed differentiation, the processes of neurodegeneration and neuroprotection as well as studies on nervous system lesion repair.
At the interface between basic Research and Public Health Services are thefive National Reference Centres (NRCs):
- the National Influenza Laboratory of Southern Greece
- the National Polio-enteroviruses Laboratory
- the National Measles and Rubella Reference Laboratory, all three recognized by the WHO
- the National Reference Centre for Leishmaniasis and
- the Reference Centre for Neisseria gonorrhoerae.
The Public Health services of HPI include a well organized Diagnostic Centre specializing in the rapid diagnosis of bacterial, viral and parasitic diseases.
The NRCs and the Diagnostic centre of HPI are in close contact with the research activities in the respective disciplines and thereby aware of the most recent developments in the diagnosis, epidemiology and treatment. This makes them exceptionally effective. On the other hand, it brings research closer to its clinical applications, strengthening translational research in HPI.
A Production Unit for Vaccines connected to a modern Quality Control Laboratory provides vaccines to the Public Sector and assessment control on vaccines and other biological products on behalf of the Greek Ministry of Health and Social Solidarity and of the National Drug Organization (EOF).
The Τechnological Facilities (Infrastructure) in HPI include the department of animal model for Biomedical Research with two important units the Transgenic technology and the Microsurgery and Transplantation, The Light microscopy Unit and the Flow cytometry unit. They all participate actively in the competitive translational and basic research projects carried out in the Intistute’s laboratories, and they provide specialized services.
Within the scope of its mission, HPI recognizes that many results are also suitable for commercialization. Thus, during the last few years, HPI has placed a special effort for the exploitation of research results and has developed strong alliances with Industry. The patent portofolio of the Institute is increasing, several R&D projects are running and some home-made diagnostic products have entered the Diagnostic Services of HPI while others are being negotiated for further development by the industry