
ΕΡΕΥΝΑ
ΔΗΜΟΣΙΕΥΣΕΙΣ (2014-2018)
Σε αυτήν την πενταετία ερευνητικά έργα που διεξάγονται σε εργαστήρια του Ελληνικού Ινστιτούτου Pasteur ή σε συνεργασία με ερευνητές άλλων ακαδημαϊκών ιδρυμάτων (εθνικών ή διεθνών) οδήγησαν σε > 250 δημοσιεύσεις σε επιστημονικά περιοδικά διεθνούς κύρους. Ο συντελεστής επίδρασης (IF) του Έτους που δημοσιεύτηκε η κάθε εργασία, όπως ανακτάται από το εργαλείο αναζήτησης BioxBio www.bioxbio.com/if/, παρουσιάζεται στον παρακάτω πίνακα:
Έτος δημοσίευσης | Μέσος IF | Εύρος IF > 5 | % Δημοσιεύσεων με IF > 5 |
---|---|---|---|
2014 | 3,581 | 5.722 - 13,309 | 23,25 |
2015 | 3,754 | 5,649 - 12,384 | 11,76 |
2016 | 5,196 | 5,071 - 20,257 | 39,06 |
2017 | 4,228 | 5,168 - 17,872 | 26,66 |
2018 | 4,426 | 6,689 - 25,148 | 25 |
O συνολικός αριθμός ετεροαναφορών για τις δημοσιεύσεις της περιόδου 2014-2018 είναι 2.307 (WoS)/2572 (Scopus). Οι δημοσιεύσεις με τις περισσότερες αναφορές παρατίθενται στον παρακάτω πίνακα:
Υψηλά αναφερόμενες δημοσιεύσεις (2014-2018) |
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Daikos GL, Tsaousi S, Tzouvelekis LS, Anyfantis I, Psichogiou M, Argyropoulou A, Stephanou I, Sypsa V, Miriagou V, Nepka M, Markogiannakis A, Goukos D, Skoutelis A. (2014). Carbapenemase-producing Klebsiella pneumoniae bloodstream infections: lowering mortality by antibiotic combination schemes and the role of carbapenems. Antimicrobial Agents & Chemotherapy; 58(4): 2322-8 (241 αναφορές) |
Sidera K, Patsavoudi E HSP90 Inhibitors (2014). Current Development and Potential in Cancer Therapy. RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY 9(1):1-20 (100 αναφορές) |
Probert L (2015). TNF and its receptors in the CNS: the essential, the desirable and the deleterious effects. J. Neuroscience 302:2-22. Review (109 αναφορές) |
Karagkouni D, Paraskevopoulou MD, Chatzopoulos S, Vlachos IS, Tastsoglou S, Kanellos I, Papadimitriou D, Kavakiotis I, Maniou S, Skoufos G, Vergoulis T, Dalamagas T, Hatzigeorgiou AG. (2018). DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA-gene interactions. Nucleic Acids Res. 46(D1):D239-D245 (26 αναφορές) |
ΕΡΕΥΝΗΤΙΚΕΣ ΔΗΜΟΣΙΕΥΣΕΙΣ (2014-2018)
Η πλήρης λίστα των δημοσιεύσεων για την περίοδο 2014-2018 είναι παρακάτω:
2014
- Agallou M., Athanasiou E., Koutsoni O., Dotsika E. and Karagouni E. (2014). Experimental Validation of Multi- Epitope Peptides Including Promising MHC Class I- and II-Restricted Epitopes of Four Known Leishmania infantum Proteins. Front Immunol. 10;5:268
- Agallou M., Dotsika E. and Karagouni E. (2014). Low CD40 expression levels in Leishmania infantum-infected bone marrow dendritic cells evokes regulatory responses by down-regulating IL-12 production: Role of ERK1/2. Eur. J. Inflammation. 12(2): 315-328
- Agallou M., Dotsika E., Frydas S. and Karagouni E. (2014) Toll-like receptor 4 promotes control of Leishmania infantum infection through inducement of leishmanicidal activity in host macrophages: role of mitogen activated kinases. J Biol Regul Homeost Agents. 28(1):41-52
- Alexandratos A, Smirlis D. (2014). Protein sample preparation for proteomic analysis in L. donovani. Bioprotocol.Org. 4 (5)
Avidan N, Le Panse R; Harbo H, Bernasconi P, Poulas K, Ginzburg E; Cavalcante P, Colleoni L; Baggi F, Antozzi C, Truffault F, Horn-Saban S, Pöschel S, Zagoriti Z, Maniaol A, Lie B; Bernard I, Saoudi A, Illes Z, Casasnovas C, Melms A, Tzartos S; Willcox N, Kostera-Pruszczyk A, Tallaksen C, Mantegazza R, Berrih-Aknin S, Miller A. (2014). VAV1 and BAFF, via NFκB pathway, are genetic risk factors for Myasthenia Gravis Annals of Clinical and Translational Neurology;1(5):329-39 - Boltsis I, Lagoumintzis G, Chatzileontiadou DSM, Giastas P, Tzartos SJ, Leonidas DD, and Poulas K. (2014). Non-contact Current Transfer Induces the Formation and Improves the X-ray Diffraction Quality of Protein Crystals. Cryst. Growth 14,9,4347-4354 https://pubs.acs.org/doi/abs/10.1021/cg5004098?journalCode=cgdefu
- Cole MJ, Spiteri G, Town K, Unemo M, Hoffman S, Chisholm SA, Amato-Gauci AJ, van de Laar M, Ison CA and the Euro-GASP Network. (2014).Risk factors for antimicrobial-Resistant Neisseria gonorrhea in Europe. Sexually Transmitted Diseases; 41(12): 723-9. Collaboration in HPI with Tzelepi E.
- Daikos GL, Tsaousi S, Tzouvelekis LS, Anyfantis I, Psichogiou M, Argyropoulou A, Stephanou I, Sypsa V, Miriagou V, Nepka M, Markogiannakis A, Goukos D, Skoutelis A. (2014). Carbapenemase-producing Klebsiella pneumoniae bloodstream infections: lowering mortality by antibiotic combination schemes and the role of carbapenems. Antimicrobial Agents & Chemotherapy; 58(4): 2322-8 (highly cited 225)
- Efstathiou A, Gaboriaud-Kolar N, Smirlis D, Myrianthopoulos V, Vougogiannopoulou K, Alexandratos A, Kritsanida M, Mikros E, Soteriadou K, Skaltsounis AL. (2014). An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial Glycogen Synthase Kinase-3 over leishmanial cdc2-related protein kinase 3. Parasit Vectors. 20;7:234.
- Foka P, Karamichali E, Dalagiorgou G, Serti E, Doumba PP, Pissas G, Kakkanas A, Kazazi D, Kochlios E, Gaitanou M, Koskinas J, Georgopoulou U, Mavromara P. (2014) Hepatitis C virus modulates lipid regulatory factor Angiopoietin-like 3 gene expression by repressing HNF-1α activity. J Hepatol. 60(1):30-8.
- Foka, P., A. Dimitriadis, E. Kyratzopoulou, D. A. Giannimaras, S. Sarno, G. Simos, U. Georgopoulou, and A. Mamalaki. (2014). A complex signaling network involving protein kinase CK2 is required for hepatitis C virus core protein-mediated modulation of the iron-regulatory hepcidin gene expression. Cellular and Molecular Life Sciences 71:4243-4258.
- Gatselis NK, Lyberopoulou A, Zachou K, Chachami G, Eliades P, Gabeta S, Paraskeva E, Mamalaki A, Koukoulis GK, Simos G, Dalekos GN. (2014. Down-regulation of hepcidin production in patients with autoimmune liver diseases Hepatology. 60: 365A-366A Supplement: 1
- Georgopoulou U, Dimitriadis A, Foka P, Karamichali E, Mamalaki A. (2014). Hepcidin and the iron enigma in HCV infection. Virulence. 5(4):465-76
- Kanistras I., A. Hatzioannou, P. Lymberi. (2014). A novel pathogenic peptide of thyroglobulin (2208–2227) induces autoreactive T-cell and B-cell responses in both high and low responder mouse strains, Immunology 142(2): 300–306
- Karamichali, E., P. Foka, E. Tsitoura, K. Kalliampakou, D. Kazazi, P. Karayiannis, U. Georgopoulou, and P. Mavromara. (2014). HCV NS5A co-operates with PKR in modulating HCV IRES-dependent translation. Infection Genetics and Evolution 26:113-122.
- Kordas G, Lagoumintzis G, Sideris S, Poulas K and Tzartos SJ. (2014). Direct proof of the in vivo pathogenic role of the nAChR autoantibodies from myasthenia gravis patients. PLOS-1 26;9(9):e108327.
- Koutsoni O., Barhoumi M., Guizani I. and Dotsika E. (2014) Leishmania Eukaryotic Initiation Factor (LeIF) Inhibits Parasite Growth in Murine Macrophages. PLoS One.15;9(5):e97319.
- Kouvatsos N, Niarchos A, Zisimopoulou P, Eliopoulos E, Poulas K, and Tzartos S. (2014). Purification and functional characterization of a truncated human α4β2 nicotinic acetylcholine receptor. Int. J Biol Macromol pii: S0141-8130(14)00441-3
- Lazaridis K, Zisimopoulou P, Giastas P, Bitzopoulou K, Evangelakou P; Sideri A, Tzartos SJ. (2014). Expression of human nAChR extracellular domain mutants with improved characteristics. Int. J Biol Macromol, 63:210-7
- Loers G, Saini V, Mishra B, Papastefanaki F, Lutz D, Chaudhury S, Ripoll DR, Wallqvist A, Gul S, Schachner M, Kaur G. (2014) Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture. J Neurochem. 128(1):88-100
- Manoussakis MN, Fragoulis GE, Vakrakou AG, Moutsopoulos HM. (2014). Impaired clearance of early apoptotic cells mediated by inhibitory IgG antibodies in patients with primary Sjögren’s syndrome. PLoS One. 14;9(11):e112100
- Marino M, Maiuri MT, Di Sante G, Scuderi F, La Carpia F, Trakas N, Provenzano C, Zisimopoulou P, Ria F, Tzartos SJ, Evoli A, Bartoccioni E. (2014). T cell repertoire in DQ5-positive MuSK-positive myasthenia gravis patients. J Autoimmun. 52:113-21
- Mavroidi A, Liakopoulos A, Gounaris A, Goudesidou M, Gaitana K, Miriagou V, Petinaki E. (2014. Successful control of a neonatal outbreak caused mainly by ST70 multidrug-resistant SHV-5-producing Klebsiella pneumoniae. BMC Pediatric; 14(1): 105
- Papagiannitsis CC, Kotsakis SD, Tuma Z, Gniadkowski M, Miriagou V, Hrabak J. (2014). Identification of CMY-2-type cephalosporinase in clinical isolates of Enterobacteriaceae by MALDI-TOF MS. Antimicrobial Agents & Chemotherapy 58(5): 2952-7
- Pogka V, Moutousi A, Kossyvakis A, Kalliaropoulos A, Sgouras DN, Giannaki M, Mentis AF.( 2014). Genetic variability of human metapneumo- and bocaviruses in children with respiratory tract infections. Influenza Other Respir Viruses. 8(1):107-15
- Prodromidou K, Papastefanaki F, Sklaviadis T, Matsas R. (2014. Functional cross-talk between the cellular prion protein and the neural cell adhesion molecule NCAM is critical for neuronal differentiation of neural stem/precursor cells. Stem Cells 32(6):1674-87
- Robotis J.F.* and Vassilaki N.* (2014). Viral Hepatitis. In Reference Module in Biomedical Sciences, edited by M. Caplan, review article Elsevier. http://dx.doi.org/10.1016/B978-0-12-801238-3.05401-5
- Schuh C, Wimmer I, Hametner S, Haider L, Van Dam A-M, Liblau RS, Smith KJ, Probert L, Binder CJ, Bauer J, Bradl M, Mahad D, Lassmann H (2014). Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models. Acta Neuropathol. 128(2):247-66
- Sidera K, Patsavoudi E (2014). HSP90 Inhibitors. Current Development and Potential in Cancer Therapy. RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY 9(1):1-20 (highly cited 91)
- Skenderi KP, Papanikolaou G, Mamalaki A., Panagiotakos DB., Kyratzopoulou E., Eliadis P., Tsironi M. (2014). Effects of prolonged and brisk exercise on iron metabolism and Hepcidin levels. Medicine and science in sports and exercise. 46, 5: 405-405, Supplement: 1
- Skriapa L, Zisimopoulou P, Trakas N, Grapsa E, Tzartos SJ. (2014). Expression of extracellular domains of Muscle Spesific Kinase (MuSK) and use as immunoadsorbents for the development of an antigen specific therapy. J. Neuroimmunol. 276(1-2):150-8
- Stellas D, Souliotis VL, Bekyrou M, Smirlis D, Kirsch-Volders M, Degrassi F, Cundari E, Kyrtopoulos SA. (2014). Benzo[a]pyrene-induced cell cycle arrest in HepG2 cells is associated with delayed induction of mitotic instability. Mutat Res 769:59-68
- Thomaidou D. (2014). Neural Stem Cells transplantation in an animal model of traumatic brain injury; Methods Mol. Biol., 1210: 9-21
- Tsiodras S, Baka A, Mentis A, Iliopoulos D, Dedoukou X, Papamavrou G, Karadima S, Emmanouil M, Kossyvakis A, Spanakis N, Pavli A, Maltezou H, Karageorgou A, Spala G, Pitiriga V, Kosmas E, Tsiagklis S, Gkatzias S, Koulouris N, Koutsoukou A, Bakakos P, Markozanhs E, Dionellis G, Pontikis K, Rovina N, Kyriakopoulou M, Efstathiou P, Papadimitriou T, Kremastinou J, Tsakris A, Saroglou G. (2014). A case of imported Middle East Respiratory Syndrome coronavirus infection and public health response, Greece, April 2014. Euro Surveill.19(16):20782
- Tsivgoulis G, Dervenoulas G, Kokotis P, Zompola C, Tzartos J, Tzartos SJ, Voumvourakis KI. (2014). Double seronegative myasthenia gravis with low density lipoprotein-4 (LRP4) antibodies presenting with isolated ocular symptoms. J. Neurol. Sci. 346(1-2):328-30
- Tsivgoulis G, Dervenoulas G, Tzartos SJ, Zompola C, Papageorgiou SG, Voumvourakis K. (2014). Double seropositive myasthenia gravis with acetylocholine receptor and lipoprotein receptor-related protein 4 antibodies. Muscle and Nerve 49(6):930-1
- Tuzun E., Tzartos J., Ekizoglu E., Stergiou C., Zisimopoulou P., Çoban A., Shugaiv E., Türkoglu R., Kürtüncü M., Baykan B., Tzartos S. (2014). Aquaporin-1 Antibody in Neuromyelitis Optica Patients. European Neurology 72(5-6):271-272
- Tzartos JS, Zisimopoulou P, Rentzos M, Karandreas N, Zouvelou V, Evangelakou P, Tsonis A, Thomaidis T, Lauria G, Andreetta F, Mantegazza R, Tzartos SJ. (2014). LRP4 antibodies in serum and CSF from amyotrophic lateral sclerosis patients. Ann. Clin Transl Neurol. 1(2):80-7
- Ulusoy C, Kim E, Tüzün E, Huda R, Yılmaz V, Poulas K, Trakas N, Skriapa L, Niarchos A, Strait RT, Finkelman FD, Turan S, Zisimopoulou P, Tzartos S, Saruhan-Direskeneli G, Christadoss P. (2014). Preferential production of IgG1, IL-4 and IL-10 in MuSK-immunized mice. Clin Immunol. 151(2):155-63
- Vingopoulou E, Siarkou V, Batzias G, Kaltsogianni F, Sianou E, Koutinas A, Saridomichelakis M, Sofianou D, Tzelepi E, Miriagou V. (2014). Emergence and persistence of multidrug-resistant Escherichia coli of canine origin harbouring blaCMY-2-IncI1/ST65 plasmid and novel ParC and ParE mutations. Journal of Antimicrobial Chemotherapy 69(8): 2076-80
- Vrolix K, Fraussen J, Losen M, Stevens J, Lazaridis K, Molenaar PC, Somers V, Bracho MA, Le Panse R, Stinissen P, Berrih-Aknin S, Maessen JG, Van Garsse L, Buurman WA, Tzartos SJ, De Baets MH, Martinez-Martinez P.(2014). Clonal heterogeneity of thymic B cells from early-onset myasthenia gravis patients with antibodies against the acetylcholine receptor. J. Autoimmunity 52:101-12
- Zis P, Argiriadou V, Temperikidis PP, Zikou L, Tzartos SJ, Tavernarakis A.(2014). Parkinson’s disease associated with myasthenia gravis and rheumatoid arthritis. Neurol. Sci. (Letter to the Editor). Published on line 2-7-2014
- Zisimopoulou P, Evangelakou P, Tzartos J, Lazaridis K, Zouvelou V, Mantegazza R, Antozzi C, Andreetta F, Evoli A, Deymeer F, Saruhan-Direskeneli G, Durmus H, Brenner T, Vaknin A, Berrih-Aknin S, Frenkian Cuvelier M, Stojkovic T, Debaets M, Losen M, Martinez-Martinez P, Kleopa KA, Zamba-Papanicolaou E, Kyriakides T, Kostera-Pruszczyk A, Szczudlik P, Szyluk B, Lavrnic D, Basta I, Peric S, Tallaksen C, Maniaol A, & Tzartos SJ. (2014). A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis. J. Autoimmunity 52:139-45
- Zouridakis M, Giastas P, Zarkadas E, Chroni-Tzartou D, Bregestovski P and Tzartos SJ. (2014). Crystal structures of the free and antagonist-bound states of the extracellular domain of human α9 nicotinic receptor. Nature Struct & Mol. Biol. 21(11):976-80
- Zouvelou V, Zisimopoulou P, Psimenou E, Matsigkou E, Stamboulis E, Tzartos SJ. nAChR-myasthenia gravis switching to double-seropositive several years after the onset. J. Neuroimmunol 267(1-2):111-2
2015
- Aravantinou-Fatorou K, Ortega F, Chroni-Tzartou D, Antoniou N, Poulopoulou C, Politis PK, Berninger B, Matsas R, Thomaidou D. (2015). Cend1 and Neurogenin2 Reprogram Mouse Astrocytes and Embryonic Fibroblasts to Induced Neural Precursors and Differentiated Neurons. Stem Cell Reports 5(3):405-18
- Arnaouteli S, Giastas P, Andreou A, Tzanodaskalaki M, Aldridge C, Tzartos SJ, Vollmer W, Eliopoulos E, Bouriotis V. (2015). Two putative polysaccharide deacetylases are required for osmotic stability and cell shape maintenance in Bacillus anthracis. J Biol Chem. 290(21):13465-78
- Azam L, Papakyriakou A, Zouridakis M, Giastas P, Tzartos SJ, McIntosh JM. (2015). Molecular Interaction of α-Conotoxin RgIA with the Rat α9α10 Nicotinic Acetylcholine Receptor. Mol Pharmacol. 87(5):855-64
- Beauté J, Zucs P, Korsun N, Bragstad K, Enouf V, Kossyvakis A, Griškevičius A, Olinger CM, Meijer A, Guiomar R, Prosenc K, Staroňová E, Delgado C, Brytting M, Broberg E; (2015). European Influenza Surveillance Network Age-specific differences in influenza virus type and subtype distribution in the 2012/2013 season in 12 European countries. Epidemiol Infect. 143(14):2950-8
- Becerra M, Boutefnouchet S, Cordoba O, Brehu L, Lamour I, Laimay F, Efstathiou A, Smirlis D, Michel S, Kritsanida M, Flores ML, Grougnet R. (2015). Antileishmanial activity of fucosterol recovered from lessonia vadosa by SFE, PSE and CPC. Phytochem Letters 11: 418–423
- Broberg E, Snacken R, Adlhoch C, Beauté J, Galinska M, Pereyaslov D, Brown C, Penttinen P; WHO European Region and the European Influenza Surveillance Network Start of the 2014/15 influenza season in Europe: drifted influenza A(H3N2) viruses circulate as dominant subtype. Euro Surveill 20(4) HPI Collaborators Mentis A. & Kossyvakis A. HPI Influenza National Reference Laboratory of S. Greece
- Cole MJ, Spiteri G, Jacobsson S, Pitt R, Grogorjev V, Unemo M; Euro-GASP Network. (2015) Is the tide turning again for cephalosporin resistance in Neisseria gonorrhoeae in Europe? Results from 2013 European surveillance. BMC Infectious Diseases; 15:321 http://dx.doi.org/10.1186/s12879-015-1013-x
HPI collaborators Tzelepi E. National Reference Laboratory of Neisseria gonorrhoeae - Evangelidou M, Karamita M, Vamvakas SS, Szymkowski DE, Probert L (2015). Altered expression of oligodendrocyte and neuronal marker genes predicts the clinical onset of autoimmune encephalomyelitis and indicates the effectiveness of multiple sclerosis-directed therapeutics. J Immunol. 192(9):4122-33
Foka, P., A. Dimitriadis, E. Karamichali, E. Kyratzopoulou, D. Giannimaras, J. Koskinas, A. Mamalaki, and U. Georgopoulou. (2015). Regulation of Hepcidin (HAMP) as driving force for macrophage-mediated Hepatis C (HCV) persistency. Journal of Hepatology 62:S579-S580 - Fragoulis GE, Vakrakou AG, Papadopoulou A, Germenis A, Kanavakis E, Moutsopoulos HM, Manoussakis MN. (2015). Impaired degradation and aberrant phagocytosis of necrotic cell debris in the peripheral blood of patients with primary Sjögren’s syndrome. J Autoimmun. 56:12-22
- Giakkoupi P, Tryphinopoulou K, Polemis M, Pappa O, Miriagou V, Vatopoulos A. (2015). Circulation of a multiresistant, conjugative, IncA/C plasmid within the nosocomial Providencia stuartii population in the Athens area. Diagnostic Microbiology & Infectious Disease; 82(1): 62-4. http://dx.doi.org/10.1016/j.diagmicrobio.2015.02.009
- Giannenas, I., Karamaligas, I., Margaroni, M., Pappas, I., Mayer, E., Encarnação, P. and Karagouni, E. (2015). Effect of dietary incorporation of a multi-strain probiotic on growth performance and health status in rainbow trout (Oncorhynchus mykiss). Fish Physiology & Biochemistry; 41(1): 119-28 https://10.1007/s10695-014-0010-0
- Hatzioannou A, Kanistras I, Mantzou E, Anastasiou E, Peppa M, Sarantopoulou V, Lymberi P, Alevisaki M. A (2015). Effect of Advanced Glycation End Products on Human Thyroglobulin’s Antigenicity as Identified by the Use of Sera from Patients with Hashimoto’s Thyroiditis and Gestational Diabetes Mellitus. Int J Endocrinol 2015:849615
- Karakasiliotis I, Mavromara P.(2015). Hepatocellular carcinoma: from hepatocyte to liver cancer stem cell. Front Physiol 6:154
Kitsati N, Liakos D, Ermeidi E, Mantzaris MD, Vasakos S, Kyratzopoulou E, Eliadis P, Andrikos E, Kokkolou E, Sferopoulos G, Mamalaki A, Siamopoulos K, Galaris D. (2015). Rapid elevation of transferrin saturation and serum hepcidin concentration in hemodialysis patients after intravenous iron infusion. Haematologica 100(3):e80-3 - Kossyvakis A, Pogka V, Melidou A, Moutousi A, Gioula G, Kalliaropoulos A, Exindari M, Emmanouil M, Horefti E, Spala G, Meijer A, Malisiovas N, Mentis AF. (2015). Challenges in antigenic characterization of circulating influenza A(H3N2) viruses during the 2011-2012 influenza season: an ongoing problem? J Clin Microbiol. 53(5):1493-9
- Kossyvakis A, Tao Y, Lu X, Pogka V, Tsiodras S, Emmanouil M, Mentis AF, Tong S, Erdman DD, Antoniadis A. (2015). Laboratory investigation and phylogenetic analysis of an imported Middle East respiratory syndrome coronavirus case in Greece. PLoS One. 10(4):e0125809.
- Kostomoiri M, Zikos C, Benaki D, Triantis C, Sagnou M, Paravatou-Petsotas M, Papadaki A, Boleti H, Papadopoulos M, Pirmettis I, Pelecanou M, Livaniou E. (2015). New labeled derivatives of the neuroprotective peptide colivelin: synthesis, characterization, and first in vitro and in vivo applications. Arch Biochem Biophys. 567:83-93.
- Kotsakis SD, Miriagou V, Vetouli EE, Bozavoutoglou E, Lebessi E, Tzelepi E, Tzouvelekis LS. (2015). Increased hydrolysis 1 of oximino-β-lactams by CMY-107, aTyr199Cys mutant of CMY-2 produced by Escherichia coli. Antimicrobial Agents & Chemotherapy 59(12): 7894-8
- Kotsakis SD, Tzouvelekis LS, Lebessi E, Doudoulakakis A, Bouli T, Tzelepi E, Miriagou V. (2015). Characterization of a mobilazable IncQ plasmid encoding the CMY-4 cephalosporinase from Escherichia coli. Antimicrobial Agents & Chemotherapy 59(5): 2964-6
- Kotta-Loizou I, Karakasiliotis I, Vassilaki N, Sakellariou P, Bartenschlager R, Mavromara P. (2015). Expression of the novel HCV core+1/ARF protein in the context of JFH1-based replicons. J. Virol. pii: JVI.02351-14
- Kusner LL, Losen M, Vincent A, Lindstrom J, Tzartos S, Lazaridis K, Martinez-Martinez P. (2015). Guidelines for pre-clinical assessment of the acetylcholine receptor-specific passive transfer myasthenia gravis model-Recommendations for methods and experimental designs. Exp Neurol 270:3-10
- Kyrargyri V, Vega-Flores G, Gruart A, Delgado-Garcia JM, Probert L. (2015). Differential contributions of microglia and neuronal IKKβ to synaptic plasticity and associative learning in alert behaving mice. Glia 63 (4): 549-566
- Lazaridis K, Evaggelakou P, Bentenidi E, Sideri A, Grapsa E and Tzartos S.J. Specific adsorbents for myasthenia gravis autoantibodies using mutants of the muscle nicotinic acetylcholine receptor extracellular domains. J. Neuroimmunol. 278:19-25
- Losen M, Martinez-Martinez P, Molenaar PC, Lazaridis K, Tzartos S, Brenner T, Duan RS, Luo J, Lindstrom J, Kusner L. S. (2015). Standardization of the experimental autoimmune myasthenia gravis (EAMG) model by immunization of rats with Torpedo californica acetylcholine receptors – Recommendations for methods and experimental designs. Exp Neurol.270:18-28
- Lyberopoulou A, Chachami G, Gatselis NK, Kyratzopoulou E, Saitis A, Gabeta S, Eliades P, Paraskeva E, Zachou K, Koukoulis GK, Mamalaki A, Dalekos GN, Simos G. (2015). Low Serum Hepcidin in Patients with Autoimmune Liver Diseases. PLoS One 10(8):e0135486
- Lykhmus O, Gergalova G, Zouridakis M, Tzartos S, Komisarenko S, Skok M. .(2015). Inflammation decreases the level of alpha7 nicotinic acetylcholine receptors in the brain mitochondria and makes them more susceptible to apoptosis induction. Int Immunopharmacol. 29(1):148-51
- Lykhmus O, Voytenko L, Koval L, Mykhalskiy S, Cholin V, Peschana K, Zouridakis M, Tzartos S, Komisarenko S and Skok M.(2015). α7 Nicotinic Acetylcholine Receptor-Specific Antibody Induces Inflammation and Amyloid β42 Accumulation In The Mouse Brain To Impair Memory. PLOS-1 10(3):e0122706
- Lytras T, Kossyvakis A, Melidou A, Exindari M, Gioula G, Pogka V, Malisiovas N, Mentis A.(2015). Influenza vaccine effectiveness against laboratory confirmed influenza in Greece during the 2013-2014 season: a test-negative study. Vaccine 33(2):367-73
- Maurer M, Bougoin S, Feferman T, Frenkian M, Bismuth J, Mouly V, Clairac G, Tzartos S, Fadel E, Eymard B, Fuchs S, Souroujon MC, Berrih-Aknin S.(2015). IL-6 and Akt are involved in muscular pathogenesis in myasthenia gravis. Acta Neuropathol Commun 3(1):1
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- Kassela K, Karakasiliotis I, Charpantidis S, Koskinas J, Mylopoulou T, Mimidis K, Sarrazin C, Grammatikos G, Mavromara P. (2017). High prevalence of antibodies to core+1/ARF protein in HCV-infected patients with advanced cirrhosis. The Journal of General Virology 98: 1713-1719
- Kossyvakis A, Mentis A-F, Tryfinopoulou K, Pogka V, Kalliaropoulos A, Antalis E, Lytras T, Meijer A, Tsiodras S, Karakitsos P, Mentis A. (2017). Antiviral susceptibility profile of influenza A viruses; keep an eye on immunocompromised patients under prolonged treatment. Eur J Clin Microbiol Infect Dis. 36(2):361-371
- Kouroupi G, Taoufik E, Vlachos IS, Tsioras K, Antoniou N, Papastefanaki F, Chroni-Tzartou, Wrasidlo W, Bohl D, Stellas D, Politis PK, Vekrellis K, Papadimitriou D, Stefanis L, Bregestovski P, Hatzigeorgiou AG, Masliah E and Matsas R. (2017). Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson’s disease. Proc Natl Acad Sci USA, 114(18):E3679-E3688
- Koutsoni OS, Routsias JG, Kyriazis ID, Barhoumi M, Guizani I, Tsakris A. and Dotsika E. (2017). In silico analysis and in vitro evaluation of immunogenic and immunomodulatory properties of promiscuous peptides derived from Leishmania infantum eukaryotic initiation factor. Bioorg Med Chem. 25(21):5904-5916.
- Kruger JM, Karussis D, Zisimopoulou P, Petrou P. (2017). Low-Density Lipoprotein Receptor-Related Protein 4-Positive Myasthenia Gravis in a Double-Seronegative, Electromyography-Negative Patient. J Neuroophthalmol. 37(3):285-286
- Kyriazis ID, Smirlis D, Papadaki A, Koutsoni O, Aligiannis N , Skaltsounis AL, Dotsika E. (2017). Leishmanicidal Activity of Oleuropein: Leishmania donovani Promastigote Cell Death through a Possibly ROS-Independent Mechanism. J Pharmacogn Nat Prod 3: 141. doi: 10.4172/2472-0992.1000141
- Lazaridis K, Dalianoudis I, Baltatzidi V, Tzartos SJ. (2017). Specific removal of autoantibodies by extracorporeal immunoadsorption ameliorates experimental autoimmune myasthenia gravis. J. Neuroimmunol. 312:24-30
- Lougiakis N., Frakolaki E., Karmou P., Pouli N.*, Marakos P., Madan V., Bartenschlager R. and Vassilaki N.* (2017). Novel nucleoside analogues targeting HCV replication through an NS5A-dependent inhibition mechanism. Chem Biol Drug 90(3):352-367
- Manoussakis MN, Mavragani CP, Nezos A, Zampeli E, Germenis A, Moutsopoulos HM.(2017). Type I interferonopathy in a young adult. Rheumatology (Oxford). 56(12):2241-2243
- Margaroni, M., Agallou, M., Athanasiou, E., Kiparissides, C., Gaitanaki, C. and Karagouni E. (2017). Vaccination with poly(D,L-lactide-co-glycolide) nanoparticles loaded with soluble Leishmania antigens and modified with TNF alpha-mimicking peptide ot monophosphoryl lipid A confers protetection against experimental visceral leishmaniasis. International Journal of Nanomedicine 12: 6169-83
- Mavroeidi P., O. Μavrofrydi, E.Pappa, M. Panopoulou, P. Papazafiri, S. Haralambous. S. Efthimiopoulos. (2017).Oxygen and glucose deprivation alter synaptic distribution of tau protein: the role of phosphorylation. J. Alzheimer disease 60: 593-604
- Mögling R, Zeller H, Revez J, Koopmans M; ZIKV reference laboratory group, Reusken C. (2017). Status, quality and specific needs of Zika virus (ZIKV) diagnostic capacity and capability in National Reference Laboratories for arboviruses in 30 EU/EEA countries, May 2016. Euro Surveill. (36)
- Moustaki M, Papadopoulos O, Verikokos C, Karypidis D, Masud D, Kostakis A, Papastefanaki F, Roubelakis MG, Perrea D. (2017). Application of adipose-derived stromal cells in fat grafting: Basic science and literature review. Exp Ther Med. 14(3):2415-2423.
- Njock GBB, Grougnet R, Efstathiou A, Smirlis D, Genta-Jouve G, Michel S, Mbing JN, Kritsanida M. (2017). A Nitrile Glucoside and Biflavones from the Leaves of Campylospermum excavatum (Ochnaceae). Chem Biodivers.14(11)
- Pallaki P, Papadimitriou E, Georganta E.M, Serafimidis I, Papakonstantinou M.P, Agalou A, Koutloglou S, Symeonof A, Tserga A, Papanikolaou V, Thomaidou D, Gaitanou M. and Georgoussi Z. (2017). A novel regulatory role of RGS4 in STAT5B activation and its effect on neural precursors proliferation and neurite outgrowth Neuropharmacology; 117:408-421
- Papaevangelou V, Christoni Z, Vliora C, Kottaridi C, Fotiou A, Malamitsi-Puchner A, Mentis A, Karakitsos P, Syggelou A. (2017). Neonatal screening for congenital CMV infection stresses the importance of maternal nonprimary infection even in an area where prenatal serology testing is common. J Matern Fetal Neonatal Med. 32(11):1901-1904.
- Papagiannitsis C, Tzouvelekis LS, Tzelepi E, Miriagou V. (2017). attI1-Located Small ORFs (ORF-17 and ORF-11) in a Class 1 Integron Affect Expression of a Gene Cassette Possessing Canonical Shine-Dalgarno Sequence. Antimicrobial Agents & Chemotherapy; 61(3). pii: e02070-16.
- Petrov AI, Kay SJE, Kalvari I, Howe KL, Gray KA, Bruford EA, Kersey PJ, Cochrane G, Finn RD, Bateman A, Kozomara A, Griffiths-Jones S, Frankish A, Zwieb CW, Lau BY, Williams KP, Chan PP, Lowe TM, Cannone JJ, Gutell R, Machnicka MA, Bujnicki JM, Yoshihama M, Kenmochi N, Chai B, Cole JR, Szymanski M, Karlowski WM, Wood V, Huala E, Berardini TZ, Zhao Y, Chen R, Zhu W, Paraskevopoulou MD, Vlachos IS, Hatzigeorgiou AG, Ma L, Zhang Z, Puetz J, Stadler PF, McDonald D, Basu S, Fey P, Engel SR, Cherry JM, Volders PJ, Mestdagh P, Wower J, Clark MB, Quek XC, Dinger ME. (2017). RNAcentral: a comprehensive database of non-coding RNA sequences. Nucleic Acids Res. 45(D1):D128-D134
- Pogka V, Labropoulou S, Emmanouil M, Voulgari-Kokota A, Vernardaki A, Georgakopoulou T2, Mentis A. (2017). Laboratory surveillance of polio and other enteroviruses in high-risk populations and environmental samples. Appl Environ Microbiol. 83(5). pii: e02872-16
- Roberts ML, Katsoupi P, Tseveleki V, Taoufik E. (2017). Bioinformatically Informed Design of Synthetic Mammalian Promoters. Methods Mol Biol.1651:93-112
- Samara P, Miriagou V, Zachariadis M, Mavrofrydi O, Promponas V, Dedos S, Papazafiri P, Kalbacher H, Voelter W, Tsitsilonis O. (2017). A fragment of the alarmin prothymosin α as a novel biomarker in murine models of bacteria-induced sepsis. Oncotarget; 8(30): 48635-49
- Saxena A, Stevens J, Cetin H, Koneczny I, Webster R, Lazaridis K, Tzartos S, Vrolix K, Nogales-Gadea G, Machiels B, Molenaar PC, Damoiseaux J, De Baets MH, Simon-Keller K, Marx A, Vincent A, Losen M, Martinez-Martinez P. (2017). Characterization of an anti-fetal nAChR monoclonal antibody isolated from a myasthenia gravis patient. Sci Rep. 7(1):14426
- Toubanaki, D.K. and Karagouni E. (2017). Genotype-specific real-time PCR combined with high-resolution melting analysis for rapid identification of red-spotted grouper nervous necrosis virus. Archives of Virology; 162(8): 2315-28
- Türkoğlu R, Lassmann H, Aker FV, Tzartos J, Tzartos S, Tüzün E. (2017). Recurrent tumefactive demyelinating lesions: a pathological study. Clin Neuropathol. 36(4):195-198
- Tzartos JS, Stergiou C, Daoussis D, Zisimopoulou P, Andonopoulos AP, Zolota V, Tzartos SJ. (2017). Antibodies to aquaporins are frequent in patients with primary Sjögren’s syndrome. Rheumatology. 56(12):2114-2122
- Vakrakou AG, Polyzos A, Kapsogeorgou EK, Thanos D, Manoussakis MN. (2017). Perturbation of transcriptome in non-neoplastic salivary gland epithelial cell lines derived from patients with primary Sjögren’s syndrome. Data Brief.17:194-199
- Vassilaki N.* and Frakolaki E. (2017). Virus-host interactions under hypoxia. Special issue: Effects of hypoxia on infection and host immune control. Microbes Infect. 19:193-203
- Vlachos IS, Hatzigeorgiou AG. (2017). Functional Analysis of miRNAs Using the DIANA Tools Online Suite. Methods Mol Biol. 1517:25-50
2018
- Georgopoulos SD, Papastergiou V, Martinez-Gonzalez B, Xirouchakis E, Familias I, Sgouras D, Mentis A, Karatapanis S. (2018). Hybrid therapy as first-line regimen for Helicobacter pylori eradication in a high clarithromycin resistance area: a prospective open-label trial. Ann Gastroenterol. 31(2):205-210
- Adlhoch, C., R. Snacken, A. Melidou, S. Ionescu, P. Penttinen, and N. (2018). The European Influenza Surveillance (2018). Dominant influenza A(H3N2) and B/Yamagata virus circulation in EU/EEA, 2016/17 and 2017/18 seasons, respectively, Euro Surveill23(13): 18-00146.
- Agallou, M., Pantazi, E., Tsiftsaki, E., Toubanaki, D.K., Gaitanaki, C., Smirlis, D. and Karagouni, E. (2018). Induction of protective cellular immune responses against experimental visceral leishmaniasis mediated by dendritic cells pulsed with the N-terminal domain of Leishmania infantum elongation factor-2 and CpG oligodeoxynucleotides. Molecular Immunology; 103: 7-20
- Angelakis E et al. (2018). Comparison of the gut microbiota of obese individuals from different geographic origins. New Microbes and New Infections. Available online 22 November 2018, 27: 40-47
- Angelakis E et al. (2018). Treponema species enrich the gut microbiota of traditional rural populations but are absent from urban individuals. New Microbes New Infect 27: 14–21 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276622/
- Bussotti G, Gouzelou E, Côrtes Boité M, Kherachi I, Harrat Z, Eddaikra N, Mottram JC, Antoniou M, Christodoulou V, Bali A, Guerfali FZ, Laouini D, Mukhtar M, Dumetz F, Dujardin JC, Smirlis D, Lechat P, Pescher P, El Hamouchi A, Lemrani M, Chicharro C, Llanes-Acevedo IP, Botana L, Cruz I, Moreno J, Jeddi F, Aoun K, Bouratbine A, Cupolillo E, Späth GF. (2018). Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification. MBio. 6;9(6)
- Chihab H, Jadid FZ, Foka P, Zaidane I, El Fihry R, Georgopoulou U, Marchio A, Elhabazi A, Chair M, Pineau P, Ezzikouri S, Benjelloun S. (2018). Programmed cell death-1 3′-untranslated region polymorphism is associated with spontaneous clearance of hepatitis B virus infection. J Med Virol. 90(11):173 0-1738
- Day MJ, Spiteri G, Jacobsson S, Woodford N, Amato-Gauci AJ, Cole MJ, Unemo M; Euro-GASP network. (2018). (Colaboration Tzelepi E.).Stably high azithromycin resistance and decreasing ceftriaxone susceptibility in Neisseria gonorrhoeae in 25 European countries, 2016. BMC Infectious Diseases; 18(1):609
- Efstathiou A, Meira CS, Gaboriaud-Kolar N, Bastos TM, Rocha VPC, Vougogiannopoulou K, Skaltsounis AL, Smirlis D*, Soares MBP*. Indirubin derivatives are potent and selective anti-Trypanosoma cruzi agents. Virulence 9(1):1658-1668
- Emmanouil, M., Tseveleki, V., Triantafyllakou, I., Nteli, A., Tselios, T., Probert, L. (2018). A Cyclic Altered Peptide Analogue Based on Myelin Basic Protein 87–99 Provides Lasting Prophylactic and Therapeutic Protection Against Acute Experimental Autoimmune Encephalomyelitis, Molecules, 23,2,304 Multidisciplinary Digital Publishing Institute
- Frakolaki E., Kaimou P., Moraiti M., Kalliampakou K. I., Karampetsou K., Dotsika E. Liakos P., Vassilacopoulou D., Mavromara P., Bartenschlager R. and Vassilaki N.* (2018). The Role of Tissue Oxygen Tension in Dengue Virus Replication. Cells 7(12), 241; Special Issue Gene Regulation by HIFs during Hypoxia
- Georgakilas G, Perdikopanis N, Hatzigeorgiou AG. (2018). Identifying Pri-miRNA Transcription Start Sites. Methods Mol Biol. 1823:11-31. doi: 10.1007/978-1-4939-8624-8_2
- Georgakopoulou T, Horefti E, Vernardaki A, Pogka V, Gkolfinopoulou K, Triantafyllou E, Tsiodras S, Theodoridou M, Mentis A, Panagiotopoulos T. (2018). Ongoing measles outbreak in Greece related to the recent European-wide epidemic. Epidemiol Infect. 8:1-7
- Giastas P, Andreou A, Papakyriakou A, Koutsioulis D, Balomenou S, Tzartos SJ, Bouriotis V, Eliopoulos EE. (2018). Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors. Biochemistry 57(5):753-763
- Harris SR, Cole MJ, Spiteri G, Sánchez-Busó L, Golparian D, Jacobsson S, Goater R, Abudahab K, Yeats CA, Bercot B, Borrego M-J, Crowley B, Stefanelli P, Tripodo F, Abad R, Aanensen DM, Unemo M, Euro-GASP study group. (2018). Public health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe: a genomic survey. The Lancet Infectious Diseases; 18(7):858-68 Tzelepi E. as a collaborator http://dx.doi.org/10.1016/S1473-3099(18)30225-1
- Ivanova II, Mihaylova NM, Manoylov IK, Makatsori D, Lolov S, Nikolova MH, Mamalaki A, Prechl J, Tchorbanov AI. (2018). Targeting of Influenza Viral Epitopes to Antigen-Presenting Cells by Genetically Engineered Chimeric Molecules in a Humanized NOD SCID Gamma Transfer Model. Hum Gene Ther 29(9):1056-1070
- Karagkouni D, Paraskevopoulou MD, Chatzopoulos S, Vlachos IS, Tastsoglou S, Kanellos I, Papadimitriou D, Kavakiotis I, Maniou S, Skoufos G, Vergoulis T, Dalamagas T, Hatzigeorgiou AG.(2018). DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA-gene interactions. Nucleic Acids Res 4;46(D1):D239-D245 (highly cited 18)
- Karamichali E., Chihab H., Kakkanas A., Marchio A., Karamitros T., Pogka V., Varaklioti A., Kalliaropoulos A., Martinez-Gonzales B., Foka P., Koskinas I., Mentis A., Benjelioun S., Pineau P., Georgopoulou U. (2018). HCV defective genomes promote persistent infection by modulating the viral life cycle. Front Microbiol 9:2942
- Karamitros T, Hurst T, Marchio E, Karamichali E, Georgopoulou U, Mentis A, Riepsaame J, Lin A, Paraskevis D, Hatzakis A, McLauchlan J, Katzourakis A, Magiorkinis G. (2018). Human Endogenous Retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line model. Proc Natl Acad Sci U S A.115(41):10434-10439
- Karamitros T, Magiorkinis G. (2018). Multiplexed Targeted Sequencing for Oxford Nanopore MinION: A Detailed Library Preparation Procedure. Methods Mol Biol. 1712:43-51
- Karamitros T, Papatheodoridis G, Paraskevis D, Hatzakis A, Mbisa JL, Georgopoulou U, Klenerman P, Magiorkinis G. (2018). Impact of Interferon-α Receptor-1 Promoter Polymorphisms on the Transcriptome of the Hepatitis B Virus-Associated Hepatocellular Carcinoma Front Immunol. 9:777
- Karamitros T, van Wilgenburg B, Wills M, Klenerman P, Magiorkinis G. (2018). Nanopore sequencing and full genome de novo assembly of human cytomegalovirus TB40/E reveals clonal diversity and structural variations. BMC Genomics 19(1):577. doi: 10.1186/s12864-018-4949-6
- Koneczny I, Rennspiess D, Marcuse F, Dankerlui N, Abdul Hamid M, Mané-Damas M, Maessen J, Van Schil P, Saxena A, Zisimopoulou P, Lazaridis K, Woodhall M, Karagiorgou K, Tzartos J, Tzartos S, De Baets MH, Molenaar PC, Marx A, Zur Hausen A, Losen M, Martinez-Martinez P. (2018). Characterization of the thymus in Lrp4 myasthenia gravis: Four cases. Autoimmun Rev. 8. pii: S1568-9972(18)30260-X
- Kotsakis SD, Flach CF, Razavi M, Larsson DGJ. (2018). Characterization of the first OXA-10 natural variant with increased carbapenemase activity. Antimicrobial Agents & Chemotherapy; pii: AAC.01817-18 https://doi.org/10.1128/AAC.01817-18
- Koutsoni OS, Karampetsou K., Kyriazis I.D., Stathopoulos P, Aligiannis N., Halabalaki M, Leandros A., Skaltsounis L.A. and Dotsika E. (2018). Evaluation of total phenolic fraction derived from extra virgin olive oil for its antileishmanial activity. Phytomedicine; 47:143-150
- Kryukova EV, Ivanov IA, Lebedev DS, Spirova EN, Egorova NS, Zouridakis M, Kasheverov IE, Tzartos SJ, Tsetlin VI. (2018). Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models. Mar Drugs 22;16(12). pii: E460
- Magiorkinis, G., T. Karamitros, T.I. Vasylyeva, L.D. Williams, J.L. Mbisa, A. Hatzakis, D. Paraskevis, and S.R. Friedman. (2018). An Innovative Study Design to Assess the Community Effect of Interventions to Mitigate HIV Epidemics Using Transmission-Chain Phylodynamics, Am J Epidemiol; 187(12): p. 2615-2622
- Maltezou, H.C., X. Dedoukou, A. Vernardaki, P. Katerelos, E. Kostea, S. Tsiodras, A. Mentis, G. Saroglou, M. Theodoridou, and T. Georgakopoulou (2018). Measles in healthcare workers during the ongoing epidemic in Greece, 2017-2018, J Hosp Infect; 100(4): p. e261-e263
- Marathe NP, Janzon A, Kotsakis SD, Flach CF, Razavi M, Berglund F, Kristiansson E, Larsson DGJ. (2018). Functional metagenomics reveals a novel carbapenem-hydrolyzing mobile beta-lactamase from Indian river sediments contaminated with antibiotic production waste. Environment International; 112:279-286
- Molyvdas A, Georgopoulou U, Lazaridis N, Hytiroglou P, Dimitriadis A, Foka P, Vassiliadis T, Loli G, Phillipidis A, Zebekakis P, Germenis AE, Speletas M, Germanidis G. (2018). The role of the NLRP3 inflammasome and the activation of IL-1β in the pathogenesis of chronic viral hepatic inflammation. Cytokine 110:389-396
- Moustafa S, Karakasiliotis I, Mavromara P. (2018). Hepatitis C Virus core+1/ARF Protein Modulates the Cyclin D1/pRb Pathway and Promotes Carcinogenesis. J Virol. 92(9). pii: e02036-17
- Mylopoulou T, Papadopoulos V, Kassela K, Karakasiliotis I, Souvalidou F, Mimidis P, Veletza S, Mavromara P, Mimidis K. (2018). Relationship between antibodies to hepatitis C virus core+1 protein and treatment outcome. Ann Gastroenterol 31(5):593-597
- Ndongo, S., M. Beye, G. Dubourg, T.T. Nguyen, C. Couderc, D.P. Fabrizio, P.E. Fournier, D. Raoult, and E. Angelakis (2018). Genome analysis and description of Xanthomonas massiliensis sp. nov., a new species isolated from human faeces, New Microbes New Infect 26: p. 63-72
- Papadopoulos N., Griveas I., Sveroni E., Argiana V., Kalliaropoulos A., Martinez-Gonzalez B., Deutsch M. (2018). HCV viraemia in anti-HCV-negative haemodialysis patients: Do we need HCV RNA detection test? Int J Artif Organs 41(3):168-170
- Papastamatiou T., Routsias JG., Koutsoni O., Dotsika E., Tsakris A. and Spoulou V. (2018). Evaluation of protective efficacy of selected immunodominant B-cell epitopes within virulent surface proteins of Streptococcus pneumonia. Infect Immun 86(3). pii: e00673-17. https://doi.org/10.1128/IAI.00673-17
- Papazian I, Voulgari-Kokota A, Kyrargyri V, Evangelidou M, Probert L. (2018). Mesenchymal stem cell protection of neurons against glutamate excitotoxicity involves reduction of NMDA-triggered calcium responses and surface GluR1, and is partly mediated by TNF. Int. J. Mol. Sci. 19(3). pii: E651. doi: 10.3390/ijms19030651
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- Ramsis T.M., Abdel Karim S.E., Vassilaki N., Frakolaki E., Kamal A.A.M., Zoidis G., Ahmed N.S. and Abadi A.H. (2018). Expanding the chemical space of anti-HCV NS5A inhibitors by stereochemical exchange and peptidomimetic approaches. ARCHIV DER PHARMAZIE (Weinheim) 351(7):e1800017 http://dx.doi.org/10.1002/ardp.201800017
- Sassone J, Papadimitriou E, Thomaidou D (2018). Regenerative Approaches in Huntington’s Disease: From Mechanistic Insights to Therapeutic Protocols Front Neurosci. eCollection 2018. doi: 10.3389/fnins.2018.00800
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- Toubanaki DK, Karagouni E. (2018). Towards a Dual Lateral Flow Nanobiosensor for Simultaneous Detection of Virus Genotype-Specific PCR Products. J Anal Methods Chem. 2018:7691014
- Trakas N, Tzartos SJ. (2018). Immunostick ELISA for rapid and easy diagnosis of myasthenia gravis. J Immunol Methods 460:107-112
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- Tsitoura E, Kazazi D, Öz-Arslan D, Sever EA, Khalili S, Vassilaki N, Aslanoglou E, Dérian N, Six A, Sezerman OU, Klatzmann D, Mavromara P. (2018). Comparison of DCs activation by virus-based vaccine delivery vectors emphasizes the transcriptional downregulation of the oxidative phosphorylation pathway. Hum Gene Ther doi: 10.1089/hum.2018.161
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Ερευνητικά Προγράμματα και Ανταγωνιστική Χρηματοδότηση 2010-2018
Κατά τη διάρκεια της προαναφερθείσας χρονικής περιόδου, οι ερευνητές της HPI κατάφεραν να προσελκύσουν χρηματοδότηση για τα ερευνητικά τους έργα από διάφορους οργανισμούς χρηματοδότησης. Το συνολικό ποσό της χρηματοδότησης και το είδος των επιχορηγήσεων παρουσιάζονται στον παρακάτω πίνακα:
Xρονική Περίοδος 2010-2018
Είδος Χρηματοδότησης | Χρηματοδότηση που διαχειρίστηκε το ΕΙΠ (€) | Χρηματοδότηση που διαχειρίστηκαν Πανεπιστημιακά Ιδρύματα ή χορηγίες (€) |
---|---|---|
Έρευνα & Ανάπτυξη / Βιομηχανικά (συνεργασία με βιομηχανίες) | 5.862.336,00 | |
Επιχορηγήσεις/Χορηγίες | 3.388.562,00 | 20.000 |
Εθνικά ανταγωνιστικά | 4.159.750,00 | 530.000 |
ΕΛΙΔΕΚ* | 939.500,00 | 249.500 |
Ευρωπαικά ανταγωνιστικά | 2.762.328,00 | 0 |
Άλλα Διεθνή | 1.659.776,00 | 96.000 |
Σύνολο | 18.772.252,00 | 895.500,00 |
* ΕΛΙΔΕΚ: Ελληνικό Ίδρυμα Έρευνας και Καινοτομίας
Αναλυτική πληροφορία για τα επιστημονικά έργα και την ανταγωνιστική χρηματοδότηση (διάρκεια, οργανισμοί χρηματοδότησης και προϋπολογισμός) κατά την περίοδο αναφοράς παρουσιάζονται στους παρακάτω πίνακες (πατήστε τα κουμπιά για να εμφανιστούν):
Ερευνητικά Προγράμματα και Aνταγωνιστική Xρηματοδότηση 2010-2018
Έχει γίνει ομαδοποίηση με βάση με τον τύπο του προγράμματος.
Project ACRONYM | Project TITLE | STARTING DATE | CLOSING DATE | BUDGET (€) |
---|---|---|---|---|
Project Type: R & D - INDUSTRIAL | ||||
ERINHA-1 | European Research Infrastructure on Highly Pathogenic Agents | 1/11/2010 | 31/8/2014 | 61.026,00 |
Cooperation Project | Synthesis of polymeric nanocarriers for targeted antigen delivery to dendritic cells | 21/10/2011 | 20/10/2014 | 270.000,00 |
AltMed | Alternative preventive and therapeutic measures in Greek mariculture | 10/1/2011 | 9/1/2014 | 59.150,00 |
Cooperation Project | Development of automated methods for hepcidin determination & exploration of the Diagnostic and Pathogenetic role in deregulation diseases of iron homeostasis | 7/1/2011 | 6/11/2014 | 296.000,00 |
Cooperation Project | Pre-clinical and Toxicology Evaluation of Immunodominant Myelin Peptides/Mimetics Conjugated with Mannan towards Clinical Phase I-II Studies: A Potential Therapeutic Vaccine Drug in the Treatment of Multiple Sclerosis (MS). | 1/1/2011 | 30/6/2014 | 585.000,00 |
Abvie Bioresearch Centre | Preclinical optimization of mAb therapies | 8/3/2011 | 2015 | 844.850,20 |
Cooperation Project | Mechanisms of Induced Pluripotency: From Transcriptional Noise to Stem Cell Therapies. | 24/10/2012 | 24/5/2015 | 444.500,00 |
Cooperation Project | Exploring new markers for diagnosis of resistance to antiplatelet drugs in patients with cardiovascular disease. Alternative therapeutic approach to the development of new antiplatelet agents | 10/1/2012 | 9/1/2015 | 150.000,00 |
BIONIAN CLUSTER | Novel inhibitors of HCV growth and biomarkers related to HCV pathogenesis and response to therapeutics’. A) A set of novel inhibitors of Hepatitis C Virus growth. B) Evaluation of microRNAs as biomarkers for HCV pathogenesis and response to anti-virals | 2013 | 2015 | 5.000,00 |
IHMA Europe Sa, Switzerland | Providing characterized gonococcal isolates for use in the evaluation of antibiotics | 2014 | 2014 | 2.900,00 |
Abbvie Pharmaceutical | Supporting its research projects against Leishmaniasis | 2014 | 2014 | 5.000,00 |
EEMH 2015 | Deregulation of lipid metabolism in HCC: The HCV paradigm | 2015 | 2015 | 15.000,00 |
Toleranzia AB | Specific immunoadsorption as therapeutic appro | 11/12/2015 | 10/12/2016 | 40.000,00 |
VERISFIELD (UK) Ltd, Pharmaceutical Co | Evaluation study under confidential private agreement for testing antimicrobial activity of antibiotic formulations | 26/11/2015 | 31/12/2015 | 6.150,00 |
ERINHA-2 | European Research Infrastructure on Highly Pathogenic Agents | 1/1/2016 | 30/6/2017 | 47.187,50 |
Asklepios Gilead Sciences Hellas | Design, synthesis and biological evaluation of novel lipophilic heterocyclic chelating agents against Hepatitis C virus | 2016 | 2017 | 5.000,00 |
Asklepios Gilead Sciences Hellas | Study of a new mechanism for the impairment of the posttranslational control | 14/4/2016 | 15/4/2018 | 20.000,00 |
Asklepios Gilead Sciences Hellas | Investigate the role of defective genomes in HCV infection | 1/3/2016 | 28/2/2018 | 12.800,00 |
Toleranzia AB | Thepapy MG- No 3 | 1/6/2017 | 30/6/2018 | 13.200,00 |
Toleranzia AB | Therapy MG-No 4 | 1/10/2017 | 30/9/2019 | 50.000,00 |
Asklepios Gilead Sciences Hellas | Characterization of new synthetic and natural compounds with broad-spectrum anti-viral activity as inhibitors of Hepatitis B virus in a normoxic cell culture model. Importance of liver normoxia for HBV replication and the efficiency of inhibitors | 24/2/2017 | 24/2/2018 | 15.000,00 |
ZOETIS HELLAS S.A. | m2B (From microbiology to Big Data) for One Health project | 1/8/2018 | 30/9/2019 | 35.000,00 |
Toleranzia AB | Preclinical assessment in animals models of antigen-specific tolerance as an immunotherapy for MG-Νο 5 | 1/6/2018 | 31/5/2020 | 72.000,00 |
Asklepios Gilead Sciences Hellas | Investigate the role of exosomes as transporters of HCV viral genome, defective HCV genomes and miRNAs in liver cancer | 19/3/2018 | 18/3/2019 | 10.000,00 |
Asklepios Gilead Sciences Hellas | HCV-mediated regulation of host lipid metabolism as a putative predisposing factor for Hepatocellular carcinoma development | 19/3/2018 | 18/3/2019 | 20.000,00 |
INSECTS FOR AQUA | Utilization of organic residues from the central market of Athens (CMFO) for the production of insect larvae protein in order to reduce dependence of sea bream and sea bass feeds from fishmeal | 21/9/2018 | 20/9/2020 | 62.736,10 |
ΠΡΟΠΤΗΝΟ-ΒΙΟΑΝΑΤΡΟΦΗ | Development of a Prototype Industrial Poultry Farming Unit | 1/12/2018 | 27/11/2020 | 23.078,00 |
NGS-PCR | Development of a PCR array for the detection of differential expressed genes associated with resistance of sea bass to b-nodavirus nervous necrosis, with potential of commercial exploitation | 21/6/2018 | 20/6/2021 | 207.100,00 |
NanoVacLeish | Development of peptide-based nanovaccines against leishmaniasis | 31/7/2018 | 30/7/2021 | 415.308,90 |
Π.Ι.Ν.Δ.Ο.Σ | Free range pastured Poultry biochemical Indicators (Novel and Dynamic) to certify Outdoor rearing Systems | 28/6/2018 | 27/6/2021 | 190.000,00 |
NeuroMarkers | NeuroMarkers Biomarkers in autoimmune neurological dieseases 6/9/2018 5/9/2021 340.440,00 | 6/9/2018 | 5/9/2021 | 340.440,00 |
BIOIRON | Hepcidin, the central regulator of iron homeostasis, as diagnostic biomarker and personalized therapeutic agent | 6/9/2018 | 5/9/2021 | 413.950,88 |
ΑΚΕΣΩ | Development of an advanced humanized mouse model for multiple sclerosis: application for pre-clinical studies and drug testing | 6/9/2018 | 5/9/2021 | 397.680,71 |
INSPIRED | INSPIRED: The National Research Infrastructure on Integrated Structural Biology, Drug Screening Efforts and Drug target functional characterization» | 14/9/2018 | 13/9/2020 | 150.000,00 |
ELIXIR-GR | Greek infrastructure for Data for Life | 1/1/2018 | 31/12/2019 | 199.000,00 |
BIOIMAGING-GR | A Greek Research Infrastructure for Visualizing and Monitoring Fundamental Biological Processes | 1/1/2018 | 31/12/2019 | 267.779,00 |
ELAI-LASERLAB | Reinforcement of the Research and Innovation Infrastructure Cooperation ELAI-LASERLAB Europe, Hiper και IPERION-CH.gr | 1/2/2018 | 31/1/2021 | 48.500,00 |
EATRIS | Infrastructure for preclinical and early-phase clinical development of drugs, therapeutics and biomedical devices | 1/1/2019 | 31/12/2021 | 62.000,00 |
Project Type: NATIONAL COMPETITIVE | ||||
L. donovani s.l. (re-)emergence and spreading in Europe: molecular typing, population genetic analysis and risk assessment | 17/8/2011 | 16/8/2013 | 15.000,00 | |
ParkinsonTransMed | Modeling Parkison 's disease by conversion of fibroblasts to dopaminergic neurons | 27/9/2012 | 31/10/2015 | 347.400,00 |
Oncohepcvir | The role of oncogenic viruses in the pathogenesis of hepatocellular carcinoma: From the HCV core/core+1 protein/host interactions to HCV-associated liver cancer. | 27/9/2012 | 31/10/2015 | 407.350,00 |
Myasthenia Gravis | Novel diagnostics and antigen-specific therapy for an model autoimmune and neurological disease myasthenia gravis | 27/9/2012 | 31/10/2015 | 360.000,00 |
Astro-Rep’ | Astroglia activation and reprogramming in brain injury and repair: an open window into the brain through intravital imaging | 1/3/2013 | 28/9/2015 | 200.000,00 |
InfaNeuTra | Infectious and neurodegenerative diseases in the 21st century: study of basic mechanisms for the development of the translational research and cutting edge technologies aiming to effective diagnosis prevention and therapy | 1/4/2013 | 31/12/2015 | 1.500.000,00 |
LeishPhosphoTox | Molecular and functional characterization of specific phosphatases from the anthropozoonotic intracellular protozoan parasites Leishmania donovani and Toxoplasma gondii and investigation of their role in the parasite interaction with host cells; Exploration of their potential as drug targets | 7/10/2013 | 31/10/2015 | 30.000,00 |
NeuroID | Development of tools for Understanding and Diagnosis of Neuroimmune Disorders | 1/2/2014 | 30/9/2015 | 180.000,00 |
Bilateral R&T Collaborations - Greece-Israel | A novel combined approach for the immunotherapy of multiple sclerosis | 26/6/2014 | 30/9/2015 | 40.000,00 |
KRIPIS II | Infectious, autoimmune and neurodegenerative diseases: study of the pathogenetic mechanisms and development of diagnostic, prognostic and therapeutic approac | 1/10/2017 | 31/10/2019 | 550.000,00 |
NODAfish | Analysis of mechanisms of immunopathogenesis in natural and experimental infections of fish with Nodavirus: importance of the infection for public health | 1/5/2012 | 30/9/2015 | 110.000,00 |
Autoimmunity | Heterogeneity of Autoimmune Diseases: Understanding of Disease-Specific and Patient-Specific Mechanisms | 1/5/2012 | 30/9/2015 | 190.000,00 |
MDND | Mitochondrial Dysfunction in Neurodegenerative Diseases | 1/5/2012 | 30/9/2015 | 120.000,00 |
EVOTRANS | Membrane transport: Structure-function and evolutionary relationships | 1/5/2012 | 30/9/2015 | 40.000,00 |
GLUCOSAD | The effect of glucose deprivation on the development of Alzheimer’s disease neuropathology | 1/3/2013 | 28/9/2015 | 70.000,00 |
NSF | NSF Development of lateral flow biosensors for virus, viral antibodies and nucleic acids detection, as a complete analysis system for environmental-threatening viruses: application on fish nervous necrosis virus (Nodavirus) as a model system 23/3/2012 22/3/2015 150.000,00 | 23/3/2012 | 22/3/2015 | 150.000,00 |
NSF | Biomarkers’ identification for the preclinical evaluation of prophylactic or/and therapeutic vaccines against visceral leishmaniasis | 1/7/2014 | 31/8/2016 | 31.800,00 |
IKYDA | Molecular characterization of specific phosphatases from the protozoan parasites Leishmania donovani and investigation of their potential as drug targets | 2014 | 2015 | 10.000,00 |
IKYDA | IKYDA Astroglia activation and reprogramming in brain injury and repair: analysis by in vivo imaging (2P-LSM) of the brain 2014 2015 10.000,00 | 2014 | 2015 | 10.000,00 |
NSF | Study of new biomarkers in hepatocellular carcinoma | 1/7/2014 | 31/8/2016 | 31.800,00 |
ELPEN | Contribution of the Helicobacter pylori CagA oncoprotein in the induction of factors involved in extracellular matrix remodeling and gastric carcinogenesis | 1/1/2014 | 31/12/2014 | 20.000,00 |
NSF | Investigation of the antiparasitic activity of drugs for the discovery of new treatments against parasitic diseases whose aetiological agents are parasites of the family of trypanosomatids | 2016 | 2017 | 20.000,00 |
NSF | Induced-neurons production through direct reprogramming of human astrocytes | 1/7/2017 | 31/8/2018 | 26.000,00 |
NSF | Investigate the role of exosomes as transporters of HCV viral genome, defective HCV genomes and miRNAs in liver cancer | 1/7/2017 | 31/8/2018 | 26.000,00 |
NFRI | Cellular Signaling and Metabolic changes in HCV infection: Identification of cellular targets involved in the development/progression of HCC | 1/8/2017 | 30/6/2019 | 19.800,00 |
NSF | Study of the effects of mutant alpha-synuclein in models of Parkinson’s disease | 15/5/2017 | 29/10/2018 | 14.700,00 |
NSF | Evaluation of novel inhibitors of Hepatitis C and related viruses and biomarkers of response to anti-viral therapeutics | 15/5/2017 | 14/5/2019 | 19.600,00 |
NFRI | Evaluation of the activity of secondary metabolites of Olea europaea against protozoa of the genus Leishmania | 1/8/2017 | 30/6/2019 | 19.800,00 |
NFRI | Structural and functional studies of nicotinic acetylcholine receptors | 19/9/2018 | 18/9/2021 | 180.000,00 |
NFRI | Microglia driven pathology and altered brain suveilance in demyelination | 20/9/2018 | 19/9/2021 | 180.000,00 |
NFRI | Mechanisms of synaptic dysfunction in human induced pluripotent stem cell based 2D-end, 3D-end models of familial Parkinson 's disease | 20/9/2018 | 19/9/2021 | 180.000,00 |
Project Type: EUROPEAN COMPETITIVE | ||||
FIGHT MG | Myasthenias, a group of immune mediated neurological diseases: from etiology to therapy | 1/12/2009 | 31/5/2014 | 601.800,00 |
NEUROSIGN | Develompment of a Center of Excellence in Neurosignalling | 1/9/2010 | 28/2/2014 | 1.869.910,00 |
CHEMBIOFIGHT | Exploring Chemical Biodiversity with Innovative Approaches for Fighting Chagas and Leismaniasis | 1/3/2011 | 28/2/2015 | 48.300,00 |
CYCLON-HIT | Nanocarriers for the delivery of Antimicrobial Agents to fight Resistance Mechanisms | 1/3/2014 | 28/2/2018 | 230.318,00 |
INSUBRIA | Knowledge development & transfer of best practise of biosafety / biosecurity / biorisk management | 1/1/2015 | 31/12/2015 | 12.000,00 |
FIGHT MG | Myasthenias, a group of immune mediated neurological diseases: from etiology to therapy | 1/12/2009 | 31/5/2014 | 601.800,00 |
Project Type: OTHER INTERNATIONAL | ||||
THERAPY-MG / MDA | Antigen specific therapeutic autoantibody depletion in Myasthenia Gravis | 1/7/2010 | 30/6/2013 | 363.510,00 |
IPIN | Hepatites | 29/3/2011 | 1/12/2013 | 20.000,00 |
BNP PARIBAS | Use of human stem cells for the treatment of neurodegenerative diseases and injuries of the brain and spinal cord. | 1/1/2011 | 31/12/2013 | 45.000,00 |
LRP4-MG / AFM | Diagnosis, prevalence and characterization of a novel myasthenia gravis subtype, LRP4-MG | 1/10/2012 | 31/12/2014 | 96.000,00 |
THERAPY-MG / AFM | Preclinical assessment of an antigen-specific therapeutic approach for MG | 1/10/2015 | 31/12/2017 | 96.000,00 |
IPIN | Structural and experimental approaches to validate Leishmania LeIF antigen as drug target and immunotherapeutic molecule | 1/1/2012 | 1/12/2013 | 13.500,00 |
IPIN | ACIP proposal for the workshop on "CNS-related infections". | 1/12/2012 | 1/12/2013 | 15.000,00 |
IPIN | Digital image processing/analysis tools in Light Microscopy: From the basics and beyond | 29/10/2012 | 30/6/2013 | 44.776,00 |
IPIN | Effect of the genetic variability of the HCV Core protein on the wnt/β-catenin signalling pathway Role in HCV- induced pathogenesis and hepatocellular carcinoma development and its regulation by the stress-related protein kinase PKR : Role in HCV- induced pathogenesis and hepatocellular carcinoma development | 1/1/2013 | 31/12/2014 | 21.500,00 |
IPIN | Evaluation of Leishmania DYRK family of kinases as molecular targets for the development of antileishmanial drugs | 1/7/2013 | 31/7/2014 | 15.000,00 |
IPIN | Viral Antigen Targeting by Genetically Engineered Chimeric Molecules | 1/1/2013 | 31/12/2015 | 10.380,00 |
IPIN | PTR 417 “Parkinsonian patient-derived dopaminergic neurons for disease modeling and drug discovery” | 1/9/2013 | 31/7/2015 | 68.000,00 |
LRP4-MG / MDA | Diagnosis and characterization of LRP4-MG, a novel myasthenia gravis subtype | 1/7/2013 | 30/6/2016 | 363.510,00 |
IPIN | LeiSHield: A new collaborative action to determine prevalence, anticipate and assess urbanization of cutaneous and visceral leishmaniasis in LeishRIIP partner countries | 1/7/2014 | 31/3/2015 | 7.000,00 |
FONDATION SANTE | An integrated genome-wide miRNA-mRNA approach in a human stem cell-based model of neurodevelopment and disease” | 1/10/2014 | 28/2/2017 | 40.000,00 |
IPIN | The many faces of Hepatitis C virus: Impact of defective genomes on pathogenesis of Liver disease by assessment of exosomes secretion | 1/1/2014 | 31/12/2015 | 20.000,00 |
IPIN | Laboratory Animals in Biomedical Research: theory and practice | 2014 | 2015 | 12.200,00 |
IPIN | Identification of broad-spectrum naturally derived inhibitors against hepatotropic viruses (DENV, YFV, HBV) under culture conditions simulating liver normoxic and metabolicmicroenvironment. The interplay between virus and hepatic normoxia as a possible disease determinant. | 1/9/2015 | 31/8/2017 | 27.000,00 |
IPIN | “PTR 2015 – session 18 – PTR 523 “Mechanisms of pathological A53T-alphasynuclein ansmission in human iPS-derived neurons” | 1/9/2015 | 31/7/2017 | 80.000,00 |
IPIN | Identification of broad-spectrum naturally derived inhibitors against hepatotropic viruses (DENV, YFV, HBV) under culture conditions simulating liver normoxic and metabolicmicroenvironment. The interplay between virus and hepatic normoxia as a possible disease determinant. | 1/9/2015 | 31/8/2017 | 27.000,00 |
IPIN | Cell biology and infection : digital image processing / analysis tools for quantitative light microscopy imaging | 1/1/2016 | 31/12/2016 | 28.000,00 |
Multiple Sclerosis Trials Collaboration | The role of cellular senescence aging in disability progression in multiple sclerosis (Multiple Sclerosis Trials Collaboration | 29/2/2016 | 28/2/2019 | 80.400,00 |
InFeSteR | In vivo models of brain infection by Gram+ bacteria: from barrier crossing to neural stem cell responses | 1/1/2017 | 31/12/2018 | 30.000,00 |
FONDATION SANTE | Elucidation of miRNA-mediated transcription and epigenetic mechanisms controlling trans-differentiation of primary astrocytes to induced-neurons | 1/3/2017 | 28/2/2018 | 20.000,00 |
FONDATION SANTE | Elucidation of miRNA-mediated transcription and epigenetic mechanisms controlling trans-differentiation of primary astrocytes to induced-neurons | 1/3/2018 | 28/2/2019 | 20.000,00 |
Επιχορηγήσεις
Project ACRONYM | Project TITLE | STARTING DATE | CLOSING DATE | BUDGET (€) |
---|---|---|---|---|
EMPEIRIKIO FOUNDATION | Generation of patient-derived induced pluripotent stem cells | 2013 | 2014 | 20.000,00 |
Ministry of Health | Influenza Reference Center | 2013 | 2017 | 339.750,00 |
Ministry of Health | Polio/Enterovirus Reference Center | 2013 | 2017 | 52.712,00 |
Ministry of Health | Measles/Rubella Reference Center | 2013 | 2017 | 11.098,00 |
LATSIS Foundation | Development and exploitation of a more true-to-life novel infectious cell culture system for HCV growth for the characterization of new anti-HCV drugs | 2013 | 2014 | 12.000,00 |
Hellenic Neuroimmunol. Academy | Antibodies to Aquaporin-1 in NMO | 1/1/2015 | 31/12/2016 | 2.000,00 |
UNIVERSITY OF GREENWICH | Study of in Vivo tumouricidal activity of novel chemotherapeutics | 1/1/2015 | 31/12/2016 | 4.800,00 |
SIEMENS | Development of Next Generation Sequencing Technology aiming to improved diagnosis, Laboratory surveillance and control of Infectious Diseases | 1/4/2015 | 31/3/2017 | 230.000,00 |
SNF | Development of innovative biological products and services for infectious and neurodegenerative diseases | 5/5/2016 | 4/5/2019 | 2.500.000,00 |
Multiple Sclerosis Trials Collaboration | The role of cellular ageing in disability progression in multiple sclerosis | 2016 | 2019 | 80.400,00 |
Donation Kampouri | Development of human monoclonal antibodies targeting cancer cells | 12/1/2018 | 11/1/2019 | 12.500,00 |
Donation Kampour | EMMPRIN biomarker in cancer | 15/1/2018 | 14/2/2019 | 37.500,00 |
National Center for Precise Medicine | 22/8/2018 | 21/8/2020 | 85.800,00 |
ΕΚΠΑΙΔΕΥΣΗ
Κατά τη διάρκεια των τελευταίων 5 χρόνων (2014-2018), σε εργαστήρια του ΕΙΠ, εκπαιδεύτηκαν και πραγματοποίησαν ερευνητικές διατριβές 71 μεταπτυχιακοί (39 MSc και 32 διδακτορικοί) και 23 προπτυχιακοί φοιτητές. Σήμερα εκτελούνται 27 ερευνητικές διατριβές και διπλωματικές εργασ(4 προπτυχιακά, 5 MSc και 17 διδακτορικά). Η πλειοψηφία των φοιτητών εγγράφηκαν στα ελληνικά πανεπιστήμια, αλλά υπάρχουν περιπτώσεις φοιτητών που έχουν εγγραφεί σε Πανεπιστήμια άλλων ευρωπαϊκών χωρών (Γαλλία, Γερμανία και Δανία).
Επιλέξτε τον πίνακα που θέλετε να δείτε:
Προπτυχιακές διπλωματικές εργασίες
Tίτλος εργασίας | Ακαδημαϊκό Ιδρυμα | Ετος υποστήριξης |
---|---|---|
Development and characterization of monoclonal antibodies against human hepcidin | National Kapodistrian University of Athens | 2014 |
Pathogenic of clinical carbapenemase-producing strains of Klebsiella pneumoniae | Technical University of Athens | 2014 |
An experimental approach towards reprogramming human fetal fibroblasts to neural progenitors | National Kapodistrian University of Athens | 2014 |
Applying diagnostic methods in an attempt to investigate the epizootiology of leishmaniasis in the great Athens area | Technical University of Athens | 2014 |
Evaluating novel inhibitors of Hepatitis C virus proliferation | National Kapodistrian University of Athens | 2015 |
Expression and functional properties of HCV core protein in neuronal cells | National Kapodistrian University of Athens | 2015 |
Investigating the role of type I in interferon the function of T lymphocytes in physiological and pathological conditions | University of Ioannina | 2015 |
Study of human hepcidin | University of Ioannina | 2015 |
In vitro reprogramming of astrocytes to neurons using miRNAs | University of Crete | 2016 |
Phenotypic characterization of Leishmania infantum parasites knocked out or over-expressing the Leishmania dual specificity tyrosine regulated kinase 1 (DYRK1), for the study of its biological role | Technical University of Athens | 2016 |
Characterization of monoclonal autoantibodies which are able to penetrate living cells: analysis of penetration parameters and assessment of the amino-acid sequence of heavy and light chain | National Kapodistrian University of Athens | 2016 |
Quantification of human Hepcidin in Biological fluids | National Kapodistrian University of Athens | 2016 |
Detection of HCV defective genomes | National Kapodistrian University of Athens | 2016 |
Evaluating the efficacy of nanoparticulate antigen delivery systems in macrophages infected with Leishmania spp. | National Kapodistrian University of Athens | 2016 |
The effect of mutant tau on the signaling pathway of the synaptic receptors NMDA | National Kapodistrian University of Athens | 2017 |
Study of natural and semisynthetic compounds for their inhibitory activity against the proliferation of Hepatitis C Virus and related Flaviviruses | National Kapodistrian University of Athens | 2017 |
Investigating the role of LinDYRK1 in Leishmania Infantum | National Kapodistrian University of Athens | 2017 |
Elucidation of mechanisms of action of regulatory miRNAs in neural induction of cortical astrocytes | National Kapodistrian University of Athens | 2017 |
Evaluation of replication inhibitors against viruses of the Flaviviridae family and characterization of their mechanisms of action by analysis of resistance mutations | National Kapodistrian University of Athens | 2017 |
Effect of pH on the development of immunoassay ELISA method for quantification of human hepcidin-25 in biological fluid | National Kapodistrian University of Athens | 2017 |
Ιmmunochemical quantification of hepcidin in biological fluid | National Kapodistrian University of Athens | 2017 |
The role of the mutated protein tau on signaling via synaptic and extrasynaptic NMDA receptors | National Kapodistrian University of Athens | 2017 |
Study of human hepcidin | National Kapodistrian University of Athens | 2018 |
Μεταπτυχιακές διατριβές (ΜSc) (σε συνεργασία με Ελληνικά και άλλων χωρών πανεπιστήμια)
Tίτλος εργασίας | Ακαδημαϊκό Ιδρυμα | Ετος υποστήριξης |
---|---|---|
Development of molecular methodology for the relative quantification of the gene expression associated with innate and adaptive immunity in the sea bass: qRT-PCR methods for cd4, cd8a and IgM genes using b-actin as a reference gene | University of Thessaly | 2014 |
Construction of lentiviral expression vectors for BM88/Cend1 and RanBPM for in vivo studies in the embryonic mouse brain | National Kapodistrian University of Athens | 2014 |
Cloning, molecular and functional characterization of the putative phosphoinositide phosphatase LdPIP22 from the parasitic protozoan Leishmania donovani | National Kapodistrian University of Athens | 2014 |
Helicobacter pylori pathogenesis: Study of the role of CagA protein in the induction of Interleukin-8 through NF-kB transcriptional activation in H. pylori infection | National Kapodistrian University of Athens | 2014 |
Behavioral and Immunohistological study of the therapeutic role of PEG-coated gold nanoparticles upon injection in a mouse model of spinal cord injury | National Kapodistrian University of Athens | 2014 |
Molecular typing of Proteus mirabilis isolates. Development of a Multi-Locus-Sequence-Typing (MLST) scheme | National Kapodistrian University of Athens | 2014 |
Histological analysis of the cerebellum in the SLC25 mutant mouse model of ataxia | National Kapodistrian University of Athens | 2015 |
Study of the role of the Mirk/Dyrk1B kinase in the developing chick spinal cord | National Kapodistrian University of Athens | 2015 |
Construction and characterization of transgenic strains of the protozoan Leishmania tarentolae for heterologous expression of the red fluorescent protein mCherry and nucleobase transporter rSNBT1 from Rattus norvegicus. | University of Montpellier | 2015 |
Evaluation of mannan-conjugated myelin antigens as an immunotherapy strategy for inducing T cell tolerance and protection against experimental autoimmune encephalomyelitis in an HLA-DR2 humanized mouse model for multiple sclerosis | Southern Denmark University, Denmark | 2015 |
Molecular pathogenesis of HCV infection: Development of a cell-based system to study the interactions between HCV and host cell nucleus | Democritus University of Thrace | 2015 |
Study of the role of T cell proliferation in the development of experimental autoimmune encephalomyelitis | National Kapodistrian University of Athens | 2015 |
The use of transgenic mice as models for Multiple Sclerosis | National Kapodistrian University of Athens | 2015 |
Molecular Biology of the protozoan parasites Leishmania donovani: Cloning of an L. infantum putative phosphatase into plasmid vectors for expression of His-tagged or mCherry-tagged protein in bacteria, mammalian and Leishmania cells. | National Kapodistrian University of Athens | 2015 |
Investigating the immunogenicity of molecules derived from Leishmania infantum parasites and the differential gene expression in T cell populations of the host | National Kapodistrian University of Athens | 2015 |
Analysis of the biological role of monoclonal natural antibodies able to penetrate living cells | National Kapodistrian University of Athens | 2016 |
The pathophysiological role of the mitochondrial protein SLC25A46 in the spinal cord and the peripheral nervous system of mutant mice | National Kapodistrian University of Athens | 2016 |
Study of the effect of LPS-induced neuroinflanmmation in the function of the neurovascular unit (NVU) of transgenic mice brain using 2-photon microscopy | National Kapodistrian University of Athens | 2016 |
Production of recombinant hepcidin and expression study of hepcidin gene in hepatoma cells in the presence of HCV core protein | National Kapodistrian University of Athens | 2016 |
Study of the in vitro effect of the total extract of polyphenols derived from extra virgin olive oil in parasites of the genus Leishmania | National Kapodistrian University of Athens | 2016 |
Study of the Mirk/Dyrk1B kinase in proliferation and differentiation in the developing embryonic chick spinal cord | National Kapodistrian University of Athens | 2016 |
Investigating the prophylactic efficacy of vaccines based on sensitized dendritic cells in an experimental visceral leishmaniasis model | National Kapodistrian University of Athens | 2016 |
Functional properties of defective genomes and capsid protein of HCV affecting virus host interaction | National Kapodistrian University of Athens | 2016 |
Response of non-neurogenic brain zones on the mechanical and chemical lesion of the adult mouse Subventricular Zone | National Kapodistrian University of Athens | 2016 |
Study of the role of T cell anergy in myelin-specific T cells upon their migration into the CNS | National Kapodistrian University of Athens | 2017 |
Developing a visceral leishmaniasis model in humanized transgenic mice | National Kapodistrian University of Athens | 2017 |
Expression in E.coli and purification of a Leishmania donovani phosphoinositide binding protein from the nexin family (LdPIBPnex) | Grenoble Alpes University | 2017 |
Regenerative potential of human iPSC-derived neural stem cells in a mouse model of neurodegeneration | National Kapodistrian University of Athens | 2017 |
Study of the induction of matrix metalloproteinase expression during Helicobacter pylori infection. Stromelysin-1 and induction of Epithelial-to-mesenchymal transition | National Kapodistrian University of Athens | 2017 |
Study of gene expression following experimental infection of gastric epithelial cells with Helicobacter pylori: Impact of DNA repair mechanisms | National Kapodistrian University of Athens | 2017 |
Cloning and molecular characterization of the secreted Phosphoinositide Binding nexin-like protein LdPIΒPnex from the protozoan Leishmania donovani | National Kapodistrian University of Athens | 2017 |
Molecular and functional characterization of the Tyrosine and phosphoinositide phosphatase LdTyrPIP_22, from the protozoan parasite Leishmania donovani. | National Kapodistrian University of Athens | 2017 |
Investigation of antigen derived peptides as a novel immunotherapy for Myasthenia Gravis | National Kapodistrian University of Athens | 2018 |
Investigation of antigen derived peptides as a novel immunotherapy for Myasthenia Gravis | National Kapodistrian University of Athens | 2018 |
Investigating the role of Aurora kinase in the parasite Leishmania spp., using transgenic strains of the parasite | National Kapodistrian University of Athens | 2018 |
Studying cellular energetic metabolism and viral replication in cultured cells infected with Flaviviridae viruses under conditions of liver normoxia and in relation to L-Dopa decarboxylase | National Kapodistrian University of Athens | 2018 |
Study the epigenetic factor LSD1 in hepatitis C virus infection | National Kapodistrian University of Athens | 2018 |
Treatment of polyarthritis with biologic agents using transgenic mouse models: Study of the combinatorial therapeutic effect of a fully humanized anti-TNF agent with oleocanthal in chronic polyarthritis, using transgenic mice | National Kapodistrian University of Athens | 2018 |
Study of the Neurovascular Unit 9NVU) of the mouse brain following systemic neuroinflammation | University of Ioannina | 2018 |
Διδακτορικές Διατριβές (PhD) (σε συνεργασία με Ελληνικά και άλλων χωρών πανεπιστήμια)
Tίτλος εργασίας | Ακαδημαϊκό Ιδρυμα | Ετος υποστήριξης |
---|---|---|
Study of molecules important for cell-cycle progression in the protozoan parasite Leishmania | University of Ioannina | 2014 |
Study of molecules implicated in the development of Leishmania and T. brucei parasites | National Kapodistrian University of Athens | 2014 |
Regulation of the expression of HCV Internal Entry Ribosome Site (IRES) | University of Patras | 2014 |
Molecular mechanisms of expression and function of the N-terminal region of HCV polyprotein | National Kapodistrian University of Athens | 2014 |
The role of the transcription factor NF-κB in neuron physiology and in diseases of the central nervous system | National Kapodistrian University of Athens | 2014 |
Study of the action of natural products against intracellular parasitic organisms. | University of Patras | 2014 |
Evaluation of the antimicrobial activity of nano-particles against multi-drug-resistant bacteria | National Kapodistrian University of Athens | 2014 |
Coexpression and study of human neuronal nicotinic acetylcholine receptor | University of Patras | 2014 |
Construction, isolation and production of human recombinant antibodies against cancer antigens | National Kapodistrian University of Athens | 2014 |
Characterization and study of biological activity of natural autoantibodies which are able to penetrate living cells | University of Ioannina | 2014 |
Mutated forms of the extracellular domains of the α4β2 neuronal nicotinic acetylcholine receptor: expression, biochemical and structural characterization | University of Patras | 2014 |
Anti-DNA monoclonal autoantibodies: interference in angiogenesis and in cytokines’ network | University of Ioannina | 2014 |
Evaluation of antigen delivery systems: cell targeting and functional differentiation | Aristotle University of Thessaloniki | 2015 |
Population genetic study for evaluating the differentiation and gene flow among Eastern Mediterranean strains of the Leishmania donovani complex | Charite, Berlin, Germany | 2015 |
Biological actions of cytokines and interferons on the T cell function: T cell specific action of IFN type I during the development of Experimental Autoimmune Encephalomyelitis | University of Ioannina | 2015 |
Synthesis of nanocarriers for targeted delivery of antigens to dendritic cells | Aristotle University of Thessaloniki | 2015 |
Interaction between innate and adaptive immunity at the level of Toll-like and TCR receptors, in infections caused by parasites of the genus Leishmania | National Kapodistrian University of Athens | 2015 |
The role of Corona viruses NL63 and HKU1, parainfluenza type 4 virus and polyomavirus WU and KI in infections of young children’s respiratory tract | National Kapodistrian University of Athens | 2015 |
Study of the molecular mechanisms underlying Leishmania spp. survival within the phagocytes of the mammalian host | University of Ioannina | 2015 |
Helicobacter pylori CagA protein pathogenesis: Role of the EPIYA phosphorylation motifs in the induction of IL-8 and morphokinetic changes in gastric epithelial cells | University of Ioannina | 2015 |
The role of Corona viruses, Human metapneumovirus, Boca viruses and rhinoviruses in infections of young children’s respiratory tract | National Kapodistrian University of Athens | 2015 |
Recombinant kinase MuSK and its use for the development of antigen specific treatment of MuSK-dependent myasthenia gravis | University of Patras | 2015 |
The role of the neurogenic molecule BM88/Cend1 on Neural Stem Cells fate determination under normal conditions and following CNS trauma | National Kapodistrian University of Athens | 2016 |
The role of cell-specific depletion of the transcription factor NF-κB in the development of inflammation and demyelination during neuroinflammatory disease of the CNS using conditionally gene-targeted mice | National Kapodistrian University of Athens | 2016 |
Evaluation of the antiviral drug susceptibility of seasonal influenza viruses in Southern Greece | National Kapodistrian University of Athens | 2016 |
Development of an experimental vaccine against intracellular pathogens | National Kapodistrian University of Athens | 2016 |
Recombinant proteins of neuromuscular junction for the development of myasthenia gravis diagnostic assays | University of Patras | 2016 |
Different roles of soluble and transmembrane TNF during the development of inflammation of the CNS | National Kapodistrian University of Athens | 2017 |
Electrophysiological and biochemical study of receptors related to central nervous system diseases | National Kapodistrian University of Athens | 2018 |
Investigation of the role of genetic variability of HCV core/core+1 proteins in HCV pathogenesis | National Kapodistrian University of Athens | 2018 |
Contribution of Helicobacter pylori virulence factors in the induction of elements regulating the structure of extracellular matrix | National Kapodistrian University of Athens | 2018 |
Design, expression and structural studies of the human neuronal acetylcholine receptor | University of Patras | 2018 |
Διατριβές σε εξέλιξη
Προπτυχιακό επίπεδο
Exosomes in HCV infection | National Kapodistrian University of Athens |
Immunoregulation of experimental leishmaniasis with combination of natural products and antiparasitic drugs | National Kapodistrian University of Athens |
Evaluation of action of Oleuropein against visceral leishmaniasis in BALB/c experimental mouse models. | National Kapodistrian University of Athens |
Importance of leismaniasis surveillance for the national and European environment: diagnostic approaches | National Kapodistrian University of Athens |
Μεταπτυχιακά διπλώματα Eιδίκευσης (ΜΔΕ, MSc)
Molecular mechanisms determining the relationship among viral infection, tissue normoxia and L-Dopa decarboxylase for hepatotropic viruses | National Kapodistrian University of Athens |
Intracellular parasitism effect to signalling of cardiac H9c2 myocytes | National Kapodistrian University of Athens |
Assessing the role of immunotherapeutic molecules in leishmaniasis | National Kapodistrian University of Athens |
Role of the epigenetic factor LSD-1 in HCC | National Kapodistrian University of Athens |
The Leishmania tarentolae organism as a model for expression of recombinant proteins from homologous (Leishmania) and heterologous (homo sapiens) organisms for purification and biochemical and functional characterization. | National Kapodistrian University of Athens |
Διδακτορικά (PhD)
Signaling networks during human iPSC differention to dopaminergic neurons | National Kapodistrian University of Athens |
Differential expression of immune genes associated with innate and adaptive immunity in experimental infections with Nodavirus in the sea bass | University of Thessaly |
Directed nerve regeneration with the use of compartmentalized synthetic nerve conduits | University of Ioannina |
Evaluation of novel inhibitors of Hepatitis C virus and biomarkers of response to anti-viral therapeutics | National Kapodistrian University of Athens |
Evaluation of the activity of secondary metabolites of Olea europaea against protozoa of the genus Leishmania. | National Kapodistrian University of Athens |
Proteolysis in Helicobacter pylori infection | National Kapodistrian University of Athens |
Study of the role of Minibrain/DyrkI kinases family in CNS development | National Kapodistrian University of Athens |
Impact of Helicobacter pylori infection on DNA repair mechanisms | National Kapodistrian University of Athens |
Novel autoantibodies as biomarkers in neurological disorders | National Kapodistrian University of Athens |
Investigation of the biological action of HCV core/core+1 proteins in hepatocellular carcinoma develpment | Democritus University of Thrace |
Study of the protective efficacy of specific anti-peptide antibodies against Streptococcus pneumoniae. | National Kapodistrian University of Athens |
Effect of chemical CNS lesions on adult neurogenesis | National Kapodistrian University of Athens |
Antibacterial activity of tigeracycline, meropenem and colistin and their combinations against Klebsiella pneumoniae clinical isolates in an in-vitro pharmacokinetic/pharmacodynamic model | National Kapodistrian University of Athens |
Phosphoinositide (PI) phosphatases and proteins with PI binding domains of Leishmania parasites: Characterization of two representative molecules and study of their role in the parasite’s life cycle and virulence. | National Kapodistrian University of Athens |
Cellular Signaling and Metabolic changes in HCV infection: Identification of cellular targets involved in the development/progression of HCC | National Kapodistrian University of Athens |
In vivo study of p. A53T alpha-synuclein mutation | National Kapodistrian University of Athens |
Epidemiology and Molecular Mechanisms of Resistance of Helicobacter pylori to antibiotics | Democritus University of Thrace |
Xορηγηθείσες Yποτροφίες (2013-2018)
Για την περίοδο αναφοράς επιτεύχθηκε χρηματοδότηση για συνολικά 15 υποτροφίες από Εθνικούς και Διεθνείς Φορείς Χρηματοδότησης για την υποστήριξη υποψηφίων διδακτόρων και μεταδιδακτορικών νέων επιστημόνων οι οποίοι εκτελούν το έργο τους στα εργαστήρια του ΕΙΠ ή για την εκπαίδευσή τους σε Διεθνή Ινστιτούτα.
Φορείς χρηματοδότησης:
- IKY: ΙΔΡΥΜΑ ΚΡΑΤΙΚΩΝ ΥΠΟΤΡΟΦΙΩΝ
- IKYDA: IKY και DAAD (Γερμανική Εταιρεία Ακαδημαϊκών ανταλλαγών)
- ΕΛΙΔΕΚ: Ελληνικό Ίδρυμα Έρευνας και Καινοτομίας
- ELPEN: Φαρμακευτική Βιομηχανία
- FENS: Network for European Neuroscience Schools
(Δίκτυο Ευρωπαϊκών Σχολείων Νευροεπιστημών)
Μεταπτυχιακές διατριβές (ΜSc) (σε συνεργασία με Ελληνικά και άλλων χωρών πανεπιστήμια)
Tίτλος εργασίας | Ακαδημαϊκό Ιδρυμα | Ετος υποστήριξης |
---|---|---|
Development of molecular methodology for the relative quantification of the gene expression associated with innate and adaptive immunity in the sea bass: qRT-PCR methods for cd4, cd8a and IgM genes using b-actin as a reference gene | University of Thessaly | 2014 |
Construction of lentiviral expression vectors for BM88/Cend1 and RanBPM for in vivo studies in the embryonic mouse brain | National Kapodistrian University of Athens | 2014 |
Cloning, molecular and functional characterization of the putative phosphoinositide phosphatase LdPIP22 from the parasitic protozoan Leishmania donovani | National Kapodistrian University of Athens | 2014 |
Helicobacter pylori pathogenesis: Study of the role of CagA protein in the induction of Interleukin-8 through NF-kB transcriptional activation in H. pylori infection | National Kapodistrian University of Athens | 2014 |
Behavioral and Immunohistological study of the therapeutic role of PEG-coated gold nanoparticles upon injection in a mouse model of spinal cord injury | National Kapodistrian University of Athens | 2014 |
Molecular typing of Proteus mirabilis isolates. Development of a Multi-Locus-Sequence-Typing (MLST) scheme | National Kapodistrian University of Athens | 2014 |
Histological analysis of the cerebellum in the SLC25 mutant mouse model of ataxia | National Kapodistrian University of Athens | 2015 |
Study of the role of the Mirk/Dyrk1B kinase in the developing chick spinal cord | National Kapodistrian University of Athens | 2015 |
Construction and characterization of transgenic strains of the protozoan Leishmania tarentolae for heterologous expression of the red fluorescent protein mCherry and nucleobase transporter rSNBT1 from Rattus norvegicus. | University of Montpellier | 2015 |
Evaluation of mannan-conjugated myelin antigens as an immunotherapy strategy for inducing T cell tolerance and protection against experimental autoimmune encephalomyelitis in an HLA-DR2 humanized mouse model for multiple sclerosis | Southern Denmark University, Denmark | 2015 |
Molecular pathogenesis of HCV infection: Development of a cell-based system to study the interactions between HCV and host cell nucleus | Democritus University of Thrace | 2015 |
Study of the role of T cell proliferation in the development of experimental autoimmune encephalomyelitis | National Kapodistrian University of Athens | 2015 |
The use of transgenic mice as models for Multiple Sclerosis | National Kapodistrian University of Athens | 2015 |
Molecular Biology of the protozoan parasites Leishmania donovani: Cloning of an L. infantum putative phosphatase into plasmid vectors for expression of His-tagged or mCherry-tagged protein in bacteria, mammalian and Leishmania cells. | National Kapodistrian University of Athens | 2015 |
Investigating the immunogenicity of molecules derived from Leishmania infantum parasites and the differential gene expression in T cell populations of the host | National Kapodistrian University of Athens | 2015 |
Analysis of the biological role of monoclonal natural antibodies able to penetrate living cells | National Kapodistrian University of Athens | 2016 |
The pathophysiological role of the mitochondrial protein SLC25A46 in the spinal cord and the peripheral nervous system of mutant mice | National Kapodistrian University of Athens | 2016 |
Study of the effect of LPS-induced neuroinflanmmation in the function of the neurovascular unit (NVU) of transgenic mice brain using 2-photon microscopy | National Kapodistrian University of Athens | 2016 |
Production of recombinant hepcidin and expression study of hepcidin gene in hepatoma cells in the presence of HCV core protein | National Kapodistrian University of Athens | 2016 |
Study of the in vitro effect of the total extract of polyphenols derived from extra virgin olive oil in parasites of the genus Leishmania | National Kapodistrian University of Athens | 2016 |
Study of the Mirk/Dyrk1B kinase in proliferation and differentiation in the developing embryonic chick spinal cord | National Kapodistrian University of Athens | 2016 |
Investigating the prophylactic efficacy of vaccines based on sensitized dendritic cells in an experimental visceral leishmaniasis model | National Kapodistrian University of Athens | 2016 |
Functional properties of defective genomes and capsid protein of HCV affecting virus host interaction | National Kapodistrian University of Athens | 2016 |
Response of non-neurogenic brain zones on the mechanical and chemical lesion of the adult mouse Subventricular Zone | National Kapodistrian University of Athens | 2016 |
Study of the role of T cell anergy in myelin-specific T cells upon their migration into the CNS | National Kapodistrian University of Athens | 2017 |
Developing a visceral leishmaniasis model in humanized transgenic mice | National Kapodistrian University of Athens | 2017 |
Expression in E.coli and purification of a Leishmania donovani phosphoinositide binding protein from the nexin family (LdPIBPnex) | Grenoble Alpes University | 2017 |
Regenerative potential of human iPSC-derived neural stem cells in a mouse model of neurodegeneration | National Kapodistrian University of Athens | 2017 |
Study of the induction of matrix metalloproteinase expression during Helicobacter pylori infection. Stromelysin-1 and induction of Epithelial-to-mesenchymal transition | National Kapodistrian University of Athens | 2017 |
Study of gene expression following experimental infection of gastric epithelial cells with Helicobacter pylori: Impact of DNA repair mechanisms | National Kapodistrian University of Athens | 2017 |
Cloning and molecular characterization of the secreted Phosphoinositide Binding nexin-like protein LdPIΒPnex from the protozoan Leishmania donovani | National Kapodistrian University of Athens | 2017 |
Molecular and functional characterization of the Tyrosine and phosphoinositide phosphatase LdTyrPIP_22, from the protozoan parasite Leishmania donovani. | National Kapodistrian University of Athens | 2017 |
Investigation of antigen derived peptides as a novel immunotherapy for Myasthenia Gravis | National Kapodistrian University of Athens | 2018 |
Investigation of antigen derived peptides as a novel immunotherapy for Myasthenia Gravis | National Kapodistrian University of Athens | 2018 |
Investigating the role of Aurora kinase in the parasite Leishmania spp., using transgenic strains of the parasite | National Kapodistrian University of Athens | 2018 |
Studying cellular energetic metabolism and viral replication in cultured cells infected with Flaviviridae viruses under conditions of liver normoxia and in relation to L-Dopa decarboxylase | National Kapodistrian University of Athens | 2018 |
Study the epigenetic factor LSD1 in hepatitis C virus infection | National Kapodistrian University of Athens | 2018 |
Treatment of polyarthritis with biologic agents using transgenic mouse models: Study of the combinatorial therapeutic effect of a fully humanized anti-TNF agent with oleocanthal in chronic polyarthritis, using transgenic mice | National Kapodistrian University of Athens | 2018 |
Study of the Neurovascular Unit 9NVU) of the mouse brain following systemic neuroinflammation | University of Ioannina | 2018 |
Διδακτορικές Διατριβές (PhD) (σε συνεργασία με Ελληνικά και άλλων χωρών πανεπιστήμια)
Tίτλος εργασίας | Ακαδημαϊκό Ιδρυμα | Ετος υποστήριξης |
---|---|---|
Study of molecules important for cell-cycle progression in the protozoan parasite Leishmania | University of Ioannina | 2014 |
Study of molecules implicated in the development of Leishmania and T. brucei parasites | National Kapodistrian University of Athens | 2014 |
Regulation of the expression of HCV Internal Entry Ribosome Site (IRES) | University of Patras | 2014 |
Molecular mechanisms of expression and function of the N-terminal region of HCV polyprotein | National Kapodistrian University of Athens | 2014 |
The role of the transcription factor NF-κB in neuron physiology and in diseases of the central nervous system | National Kapodistrian University of Athens | 2014 |
Study of the action of natural products against intracellular parasitic organisms. | University of Patras | 2014 |
Evaluation of the antimicrobial activity of nano-particles against multi-drug-resistant bacteria | National Kapodistrian University of Athens | 2014 |
Coexpression and study of human neuronal nicotinic acetylcholine receptor | University of Patras | 2014 |
Construction, isolation and production of human recombinant antibodies against cancer antigens | National Kapodistrian University of Athens | 2014 |
Characterization and study of biological activity of natural autoantibodies which are able to penetrate living cells | University of Ioannina | 2014 |
Mutated forms of the extracellular domains of the α4β2 neuronal nicotinic acetylcholine receptor: expression, biochemical and structural characterization | University of Patras | 2014 |
Anti-DNA monoclonal autoantibodies: interference in angiogenesis and in cytokines’ network | University of Ioannina | 2014 |
Evaluation of antigen delivery systems: cell targeting and functional differentiation | Aristotle University of Thessaloniki | 2015 |
Population genetic study for evaluating the differentiation and gene flow among Eastern Mediterranean strains of the Leishmania donovani complex | Charite, Berlin, Germany | 2015 |
Biological actions of cytokines and interferons on the T cell function: T cell specific action of IFN type I during the development of Experimental Autoimmune Encephalomyelitis | University of Ioannina | 2015 |
Synthesis of nanocarriers for targeted delivery of antigens to dendritic cells | Aristotle University of Thessaloniki | 2015 |
Interaction between innate and adaptive immunity at the level of Toll-like and TCR receptors, in infections caused by parasites of the genus Leishmania | National Kapodistrian University of Athens | 2015 |
The role of Corona viruses NL63 and HKU1, parainfluenza type 4 virus and polyomavirus WU and KI in infections of young children’s respiratory tract | National Kapodistrian University of Athens | 2015 |
Study of the molecular mechanisms underlying Leishmania spp. survival within the phagocytes of the mammalian host | University of Ioannina | 2015 |
Helicobacter pylori CagA protein pathogenesis: Role of the EPIYA phosphorylation motifs in the induction of IL-8 and morphokinetic changes in gastric epithelial cells | University of Ioannina | 2015 |
The role of Corona viruses, Human metapneumovirus, Boca viruses and rhinoviruses in infections of young children’s respiratory tract | National Kapodistrian University of Athens | 2015 |
Recombinant kinase MuSK and its use for the development of antigen specific treatment of MuSK-dependent myasthenia gravis | University of Patras | 2015 |
The role of the neurogenic molecule BM88/Cend1 on Neural Stem Cells fate determination under normal conditions and following CNS trauma | National Kapodistrian University of Athens | 2016 |
The role of cell-specific depletion of the transcription factor NF-κB in the development of inflammation and demyelination during neuroinflammatory disease of the CNS using conditionally gene-targeted mice | National Kapodistrian University of Athens | 2016 |
Evaluation of the antiviral drug susceptibility of seasonal influenza viruses in Southern Greece | National Kapodistrian University of Athens | 2016 |
Development of an experimental vaccine against intracellular pathogens | National Kapodistrian University of Athens | 2016 |
Recombinant proteins of neuromuscular junction for the development of myasthenia gravis diagnostic assays | University of Patras | 2016 |
Different roles of soluble and transmembrane TNF during the development of inflammation of the CNS | National Kapodistrian University of Athens | 2017 |
Electrophysiological and biochemical study of receptors related to central nervous system diseases | National Kapodistrian University of Athens | 2018 |
Investigation of the role of genetic variability of HCV core/core+1 proteins in HCV pathogenesis | National Kapodistrian University of Athens | 2018 |
Contribution of Helicobacter pylori virulence factors in the induction of elements regulating the structure of extracellular matrix | National Kapodistrian University of Athens | 2018 |
Design, expression and structural studies of the human neuronal acetylcholine receptor | University of Patras | 2018 |
Περίοδος (2013-2018)