Department of Microbiology

The study of Infectious Diseases constitutes an important activity for HPI, with pioneering contributions in the field. HPI is nationally and internationally recognized for its high-level and competitive research in selected areas of Microbiology covering a selected number of pathogens with high socio-economic impact on National and European level. These include: Hepatitis C virus (HCV), Herpes viruses, protozoa Leishmania and Trypanosoma brucei, multi-resistant Gram-negative nosocomial pathogens, Neissseria gonorrhea and Helicobacter pylori.

Research in these fields is focused on:

  • the molecular and cellular biology of the above listed pathogens, with particular emphasis on the identification of pathogens’ molecules involved in growth and virulence,
  • the mechanisms determining pathogen-host interactions critical in disease progression, with specific emphasis on mechanisms controlling pathogen evasion of the hosts’ immune system,
  • identification of  key molecules implicated in pathogen-host interactions aiming to unveil new therapeutic targets for the development of antimicrobial compounds and/or immunotherapeutic or prophylactic vaccines and improvement of diagnostic tools for the prevention and control of infectious diseases,
  • studies on the molecular basis of bacterial resistance to antibiotics, with special emphasis given to the biochemical, molecular, and genetic analysis of the underlying mechanisms of bacterial resistance, as well as to the monitoring of the epidemiological trends of resistance. The latter areas of research are important for either the design of novel antimicrobial molecules and the adoption of antibiotic restriction policies for preserving the effectiveness of the existing compounds,
  • development of molecular tools for diagnosis, typing and population genetic analysis of viral, bacterial and parasitic infections. Implementation of the new technology in the Public Health Laboratories.
  • development of algorithms, databases and tools for the interpretation and archiving of genomic data. Computational predictive models are a key element of current systems biology. Functional analysis of microRNAs and protein coding genes and the human microbiota analysis.

A number of research activities in bacteria, viruses and protozoan parasites within the Microbiology laboratories are bridged with research and service activities in the Diagnostic Department and the Laboratories of the Public Health Sector. This interaction has an important impact on the development of research and services in HPI and represents a unique feature distinguishing the HPI from the other National Research Centers with an interest in research in Infectiology.

Members

Researchers

Evdokia Karagouni

Research Director,
Head of the Department of Microbiology,
Laboratory of Cellular Immunology

Vivi Miriagou

Research Director,
Laboratory of Bacteriology

Andreas Mentis

Research Director,
Head of the Medicinal Microbiology Laboratory

Dionyssios Sgouras

Research Director, PhD
Laboratory of Medical Microbiology

Eva Tzelepi

Research Director,
Head of Bacteriology Laboratory

Eleni Dotsika

Research Director,
Head of Cellular Immunology Laboratory

Haralabia Boleti

Principal Investigator,
Head of the Molecular Parasitology Laboratory – Intracellular Parasitism Group
Co-head Light Microscopy Facility

Despina Smirlis

Laboratory of Molecular Parasitology

Urania Georgopoulou

Research Director,
Molecular Virology Laboratory

Niki Vassilaki

Molecular Virology Laboratory

Collaborating Faculty Members

Artemis Hatzigeorgiou

Head of Bioinformatics Laboratory

Research Staff Scientist

Athanasios Kakkanas

Laboratory of Molecular Virology

Beatriz Martinez-Gonzalez

Staff Research Scientist Grade B
Laboratory of Medical Microbiology

Ειδικοί Τεχνικοί Επιστήμονες

Olga Koutsoni

Biologist, PhD
Cellular Immunology Laboratory

Panagiotis Psarrakos

Biologist, PhD
Laboratory of Medicinal Microbiology

Technical Personnel

Elina Aslanoglou

Laboratory of Molecular Virology

Irini Siatravani

Laboratory of Bacteriology

Post-doctoral Fellows

Maria Agallou

Biologist (ΙΔΟΧ- ΝΙΑΡΧΟΣ),
Laboratory of Cellular Immunology (Dr. Karagouni)

Timokratis Karamitros

Biologist (ΙΔΟΧ- ΝΙΑΡΧΟΣ),
Laboratory of Medicinal Microbiology (Dr. Mentis)

Stathis Kotsakis

Biologist (ΙΔΟΧ- ΝΙΑΡΧΟΣ),
Laboratory of Bacteriology (Dr. Miriagou)

PhD Students

George Miliotis

Biologist (Marie Curie),
Laboratory of Bacteriology (Dr. Miriagou)

Πτυχιούχοι

Zisis Dimitrios

Laboratory of Bioinformatics (Prof. Hatzigeorgiou)
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