Publication in the high impact journal eLife
Researchers of the Laboratory of Cellular and Molecular Neurobiology – Stem Cells and the Human Stem Cell Unit published a study in eLife in which they identified a novel small non-coding RNA, miR-934, that plays an important role during early development of the human brain and the generation of human neurons. The work, which was performed in a model of human embryonic stem cells simulating human brain development, was done in collaboration with the Bioinformatics group DIANA-Lab of the Hellenic Pasteur Institute and Beth Israel Deaconess Medical Center, Boston, and highlights the evolutionary role of this microRNA in human and non-human primate neurogenesis.
MicroRNA-934 is a novel primate-specific small non-coding RNA with neurogenic function during early development.
Prodromidou K, Vlachos IS, Gaitanou M, Kouroupi G, Hatzigeorgiou AG, Matsas R.
Elife. 2020 May 27;9:e50561. doi: 10.7554/eLife.50561.