Published in the journal PNAS

An innovative model of induced human neurons from patients with hereditary Parkinson’s disease reveals new neuropathological features of the disease and incomplete synaptic connectivity of the neuronal network.

Researchers of the Laboratory of Cellular and Molecular Neurobiology Georgia Kouroupi, Era Taoufik, Rebecca Matsas and colleagues recently published a  study in PNAS:
Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson’s disease.
(Kouroupi G, Taoufik E, Vlachos IS, Tsioras K, Antoniou N, Papastefanaki F, Chroni-Tzartou D, Wrasidlo W, Bohl D, Stellas D, Politis PK, Vekrellis K, Papadimitriou D, Stefanis L, Bregestovski P, Hatzigeorgiou AG, Masliah E, Matsas R.)

Proc Natl Acad Sci U S A.