Laboratory of Medical Microbiology

Dionyssios Sgouras | Department of Microbiology

Research Director


210-6478824 | .img@.img |  CV


Research in the LMM is centered on mechanisms by which mainly bacterial, but also viral pathogens can manifest their pathogenic role. The model organism studied is the human gastric pathogen Helicobacter pylori, which has been recognized as the etiologic factor for the development of chronic gastritis and peptic ulcer and has been classified as the primary risk factor for the development of gastric adenocarcinoma (class 1 carcinogen, by WHO). LMM functions as a National Reference Laboratory for Helicobacter infections, since present activities fully extend to diagnosis of the infection, laboratory surveillance of antimicrobial susceptibility of clinical isolates, full virulence factor characterization in H. pylori isolates, phylogenetic analysis of clinical isolates, based on specific gene or whole genome sequencing and preservation of a complete Biobank of clinical strains. LMM staff has participated in the team of microbiology experts set by the Hellenic Society of Gastroenterology, for the preparation of the consensus statement on the diagnosis, clinical management and treatment of H. pylori infection, in Greece (Georgopoulos et al., Hellenic consensus on Helicobacter pylori infection. Ann Gastroenterol. 2020)


Main scientific directions include:

Study into the mechanisms of Helicobacter pylori pathogenesis

Tissue remodeling of the extracellular matrix, through the induction of matrix metalloproteinases (MMPs) in the H. pylori infection. Identification and mapping of basic signaling pathways that lead to the activation of the particular MMP-specific or MMP-related determinants and promote Epithelial- to-Mesenchymal-Transition (EMT) (I. Karayiannis PhD project; Karayiannis in preparation 2022).

Impact of Helicobacter pylori infection in the deregulation of DNA damage response mechanisms (E. Kontizas PhD project, Kontizas et al., Microorganisms 2020; Kontizas et al., Microb Health Dis 2021) and collaboration with Dr. Eliette Touati, Institut Pasteur, Unité de Pathogenèse de Helicobacter), collaborative PTR-332 program

CagA-dependent microRNA-mediated post-transcriptional regulation of gastric epithelial cells in Helicobacter pylori infection (E. Sotiropoulou PhD project; Sotiropoulou et al., in preparation 2022)

Laboratory surveillance of H. pylori antibiotic susceptibility to common antibiotics used in the patient eradication schemes in collaboration with Alexandra, Evangelismos, Laikon, Aghia Sophia Children Hospital, Mitera Hospital, Athens Medical, Paleo Faliron Hospital Gastroenterology Clinics in Athens (in collaboration with Dr. B. Martinez-Gonzalez) and participation in prospective clinical studies for the evaluation of eradication efficiency (Georgopoulos et al. Ann Gastroenterol 2018; Georgopoulos et al. Eur J Intern Med 2016; Georgopoulos et al. Helicobacter 2013)

Phylogenetic analysis of H. pylori clinical isolates and mapping of human migrations through history. An international collaborative effort to analyze genetic variation in H. pylori genome sequences and thereby determine the phylogeographic pattern of human migrations. Collaboration with Dr. Daniel Falush, Institut Pasteur Shanghai (Thorpe et al. bioRxiv, doi:

Whole genome sequencing analysis of H. pylori clinical isolates from gastrointestinal tumors and identification of molecular features that contribute to pathology by comparing the profile of benign infection to corresponding spectra of isolates from individuals with gastric cancer and premalignant lesions such as, atrophic gastritis and intestinal metaplasia. Collaboration with Dr. M. C. Camargo and Dr. C. Rabkin MD, Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Institutes of Health, USA. (In collaboration with Dr. Martinez-Gonzalez)

Assessment of putative anti-bacterial and anti-inflammatory activity of new drugs, natural products and probiotics utilizing in vitro and in vivo infection systems. Collaboration with Prof. E. Tsakalidou of the Agricultural University of Athens on the identification and isolation of probiotic lactobacilli from traditional food sources (Saliba et al. International Dairy Journal 2021; Mangia et al. Fermentation 2019) and study of the effect of Chios mastic gum effect on the oral microbiome (Collaboration with Prof. A Hatzigeorgiou and Dr. Martinez-Gonzalez at HPI– The Schinos project)

Laboratory surveillance and phylogenetic analysis of viruses and parasites in collaboration with the Public Health laboratories of HPI. Phylogenetic analysis of respiratory viruses (Collaboration with Dr. A. Mentis until 2020 and Dr. U Georgopoulou since 2021) and Hepatitis C virus (in collaboration with Dr.Martinez-Gonzalez)

Established research tools within the laboratory include:

  • In vitro H. pylori infection systems utilizing clinical and laboratory-adapted and/or mutated bacterial strains infecting a number of gastric epithelial cell lines (AGS, N-87, MKN45, GES-1)
  • pylori in vivo animal models (Sydney Strain 1, HPARE, PMSS1 strains in C57BL6 mice), histopathological evaluation of associated gastritis by the modified Sydney System.
  • Biobank of pylori clinical isolates with matching gastric biopsies and blood samples from symptomatic patients (adults and children), with complete history of clinical symptoms and gastrointestinal pathology reports.
  • Microarray and RNAseq analysis of experimentally infected gastric epithelial cell lines infected by laboratory-adapted and/or mutated bacterial strains.

Public Health Services 

During emerging epidemics and or pandemics, LMM staff provides support in the development and implementation of novel molecular diagnostic tools and appropriate standard operating procedures for the genetic characterization and the phylogenetic/phylodynamic analysis of viral, bacterial and parasitic infections. For this purpose, LMM has developed novel methods for the metagenomic determination of the composition of microbial communities, based on next generation sequencing technologies. In addition, members of LMM (Dr. Sgouras, Dr. Mentis) have participated through FP7-INFRASTRUCTURES-2010-1, in the preparative phase of the European Research Infrastructure for Highly Pathogenic Agents (ERINHA), pursuing the implementation of a distributed pan-European high security research infrastructure for research on suspected risk group-4 pathogens. This has provided the LMM staff with the opportunity to access expertise, capacities and functions required when coming in contact with risk group-4 and/or unknown pathogens and to obtain training in procedures working at high containment. Consequently, LMM has participated through ERINHA2 H2020-INFRADEV-1-2015-2 in the preparative phase of the ERINHA framework and the research portfolio. LMM staff has also participated actively during the SARS-CoV2 pandemic supporting the Diagnostic Services in the identification of active cases.



PTR-332: CoPyMe E. coli and H. pylori as models for the role of DNA methylation in the relation between bacteria and cancer” 1/1/2021-31/12/2022 Institut Pasteur (Paris, France).
Hellenic Society of Gastroenterology Grant “Study of antimicrobial susceptibility of Helicobacter pylori with the use of phenotypic and molecular methods” 2018-2019 Hell. Soc. of Gastroenterology

22,558 €

Vaccine Unit Restructuring 2017-2020 Stavros Niarchos Foundation 810,000 €
Helicobacter pylori Genome Project: understanding a bacterial carcinogen. International collaborative project funded by the National Institutes of Health and the National Cancer Institute 2016-2017 (NIH/NCI) intramural program, USA


ERINHA2 (689622) “European Research Infrastructure on Highly Pathogenic Agents”, H2020-INFRADEV-1-2015-2. 2015-2017 EU 45,187 €
SIEMENS Hellenic Pasteur Institute Business Plan for the development of Next Generation Sequencing Technology aiming to improved diagnosis, laboratory surveillance and control of Infectious Diseases 2015-2017 GSRT 230,000 €
Hellenic H. pylori Study Group National Multicenter Laboratory Surveillance Study on antibiotic susceptibility of Helicobacter pylori. 2012-2016 Hell. Soc. of Gastroenterology and the HHPSG
InfeNeuTra-2012 (MIS-450598) “Infectious and neurodegenerative diseases in the 21st  Century:  Basic Mechanisms to translational research for diagnosis, prevention and therapy” 2012-2015 GSRT
CagAECM-Contribution of Helicobacter pylori CagA oncoprotein in the induction of factors involved in extracellular matrix remodeling and gastric carcinogenesis 2012-2014 Hellenic Soc. Gastrointestinal Oncology 20.000 €
ERINHA—European Research Infrastructure on Highly Pathogenic Agents, FP7-INFRASTRUCTURES-2010-1 2010-2013 EU 91.254 €
EHSG-Third European Multicentre Study on antibiotic susceptibility of Helicobacter pylori. 2008-2010. European Helicobacter Study Group (EHSG).
ERA-NET Parasite and host genetic diversity in Helicobacter infections 2007-2010 EU 14,656 €
Qualitative determination of viral load in the serum of patients with chronic Hepatitis C infection 2005-2007 Schering-Plough 45,000 €
Quantitative determination of viral load and/or viral genotype in the serum of patients with chronic Hepatitis C infection Schering-Plough

160,000 €

ACIP Etude de la fréquence de l’infection par Helicobacter pylori (Hp) des patients présentant une pathologie gastro-duodénale, de la sensibilité des souches aux antibiotiques et de la diversité de la région 3’ du gène cagA. 2007-2008 Institut Pasteur Paris

8,214 €

CagA motogenic effects induced on gastric epithelial cells upon H. pylori infection in vitro. Study on the interaction of CagA with PLC and effect on intracellular Ca2+ levels. 2004-2006 Hellenic Pasteur Institute

13,500 €

PROPATH Molecular analysis and mechanistic elucidation of the functionality of pro- and prebiotics in the inhibition of pathogenic micro-organisms to combat gastrointestinal disorders and to improve human health 2001 – 2004 EU 5TH Framework program

264,124 €

British Council Epidemiology and guidelines for the control of pathogens Campylobacter and  Salmonella in the poultry industry 2001 – 2002 British Council

4,500 €

PAVET – LAVIPHARM. Study of biologically active substances with potential antimicrobial and healing activity isolated from traditional plant origin 2001 – 2003 GSRT*

14,674 €

97 DIATRO-26-Development of new type of yogurt with probiotic properties – Effect on health 1999 – 2001 GSRT*
European multi-center study to monitor antibiotic resistance to H pylori in children 2000-2001 ΕU
Relationship of gastric cancer to diet and H. pylori status 1999-2001 Pasteur Institute Greece
1998 Εuropean Multicenter in vitro study on antimicrobial resistance in H. pylori 1998-1999 ΕU
Incidence of Escherichia coli virulent strains in food specimens. Detection of virulence factors. 1998-1999 Institute Pasteur, France
cagA και vacA subtypes of H. pylori clinical strains in the child population with gastritis 1998-1999 Hellenic Ministry of Health
Development of immunodiagnostic kits for antidody detection of CMV, Toxoplasma, Rubella and Helicobacter pylori. 1998-1999 GSRT*


Development of health services provided by the Diagnostic and Vaccines Quality Control Section of Hellenic Pasteur Institute to the industry 1998-2000 GSRT*


Early inhibition of sepsis: Development of methods controlling molecular mechanisms of signal transduction via tyrosine kinases and reactive oxidative substances. 1999-2000 GSRT*


Eurohepygast: Evolution of the stomach with chronic gastritis with a particular emphasis on disease markers for peptic ulcer and premalignant conditions 1997-1999 BIOMED I (ΕU)
European research network on congenital toxoplasmosis, Working group on Standardisation and quality assurance 1997-1999 ΒIOMED Ι (ΕU)

*GSRT: General Secretariat for Research and Technology, Ministry of Education



Diechler S, Chichirau BE, Posselt G, Sgouras DN, Wessler S. (2021). Helicobacter pylori CagA EPIYA Motif Variations Affect Metabolic Activity in B Cells. Toxins (Basel); 13(9):592. doi: 10.3390/toxins13090592.

Bousali, M., Dimadi, A., Kostaki, E.-G., Tsiodras, S., Nikolopoulos, G.K., Sgouras, D.N., Magiorkinis, G., Papatheodoridis, G., Pogka, V., Lourida, G., Argyraki, A., Angelakis, E., Sourvinos, G., Beloukas, A., Paraskevis, D., Karamitros, T. (2021) SARS‐CoV‐2 molecular transmission clusters and containment measures in ten European regions during the first pandemic wave. Life; 11 (3), 219, doi: 10.3390/life11030219.

Saliba L., Zoumpopoulou G., Anastasiou R., Hassoun G., Karayiannis Y, Sgouras D., Tsakalidou E., Deiana P., Montanari L. and Mangia N.P. (2021) Probiotic and safety assessment of Lactobacillus strains isolated from Lebanese Baladi goat milk International Dairy Journal; 120, 105092.

Kontizas, E. and D. N. Sgouras. “Review – Pathogenesis of Helicobacter pylori infection” (2021) Microb Health Dis; 3: e539 part of the Special Issue: The Year in Helicobacter 2021, 34th International Work-shop on Helicobacter & Microbiota in Inflammation & Cancer Virtual Conference, 12 September 2021


Kontizas, E.; Tastsoglou, S.; Karamitros, T.; Karayiannis, Y.; Kollia, P.; Hatzigeorgiou, A.G.; Sgouras, D.N. (2020). Impact of Helicobacter pylori Infection and Its Major Virulence Factor CagA on DNA Damage Repair Microorganisms; 8(12), 2007.


Mangia, N.P.; Saliba, L.; Zoumpopoulou, G.; Chessa, S.; Anastasiou, R.; Karayiannis, Ι.; Sgouras, D.; Tsakalidou, E.; Nudda, A. (2019) Goat Milk with Different Alpha-s1 Casein Genotype (CSN1S1) Fer-mented by Selected Lactobacillus paracasei as Potential Functional Food. Fermentation; 5, 55.


Georgopoulos SD, Papastergiou V, Martinez-Gonzalez B, Xirouchakis E, Familias I, Sgouras D, Mentis A, Karatapanis S. (2018) Hybrid therapy as first-line regimen for Helicobacter pylori eradication in a high clarithromycin resistance area: a prospective open-label trial. Ann Gastroenterol. Mar-Apr; 31(2):205-210. doi: 10.20524/aog.2017.0221.


Bugaytsova J, Chernov YA, Gideonsson P, Henriksson S, Mendez M, Sjöström R, Mahdavi J, Shev-tsova A, Quintana-Hayashi M, Ilver D, Moskalenko R, Aisenbrey C, Bylund G, Schmidt A, Moonens K, Björnham O, Brännström K, Königer V, Vikström S, Rakhimova L, Ögren L, Hofer A, Liu H, Goldman M, Whitmire JM, Younson JS, Kelly CG, Gilman RH, Chowdhury A, Mukhopadhyay AK, Nair BG, Papadakos KS, Martinez-Gonzalez B, Sgouras DN, Engstrand L, Unemo M, Danielsson D, Suerbaum S, Oscarson S, Morozova-Roche L, Gröbner G, Holgersson J, Esberg A, Strömberg N, Eldridge A, Chromy BA, Hansen LM, Solnick JV, Schedin S, Lindén SK, Haas R, Dubois A, Merrell DS, Remaut H, Arnqvist A, Berg DE, Borén T. (2017) Adaptation of the oncopathogen H. pylori during chronic in-fection and to gastric disease by acid responsive adherence Cell Host & Microbe. Mar 8;21(3):376-389, doi: 10.1016/j.chom.2017.02.013


Georgopoulos SD, Xirouchakis E, Martinez-Gonzalez B, Zampeli E, Grivas E, Spiliadi C, Sotiropoulou M, Petraki K, Zografos K, Laoudi F, Sgouras D, Mentis A, Kasapidis P, Michopoulos S. (2016) Ran-domized clinical trial comparing ten day concomitant and sequential therapies for Helicobacter pylori eradication in a high clarithromycin resistance area. Eur J Intern Med. pii: S0953-6205(16)30080-2. doi: 10.1016/j.ejim.2016.04.011.

Costa AM, RM Ferreira, I Pinto-Ribeiro, IS Sougleri, MJ Oliveira, L Carreto, MA Santos, DN Sgouras, F Carneiro, M Leite and C Figueiredo (2016) Helicobacter pylori activates matrix metalloproteinase-10 in gastric epithelial cells via EGFR and ERK-mediated pathways. J Infect Dis. 213(11): 1767-76 doi: 10.1093/infdis/jiw031


Sougleri IS, KS Papadakos, MP Zadik, M Mavri-Vavagianni, AF Mentis and DN Sgouras (2015) Heli-cobacter pylori CagA protein induces factors involved in the Epithelial-to–Mesenchymal-Transition (EMT) in infected gastric epithelial cells in an EPIYA- phosphorylation-dependent manner. FEBS J. 283(2): 206-220 doi: 10.1111/febs.13592

Sgouras DN, Trang TT, Yamaoka Y. (2015) Pathogenesis of Helicobacter pylori Infection. Helicobac-ter. Sep;20 Suppl 1:8-16. doi: 10.1111/hel.12251.


Tropcheva R, Hristova J, Georgieva R, Salageanu A, Sgouras DN, Danova S (2013) In vitro assess-ment of prebiotic utilization by dairy lactobacilli. Bulgarian J. Agric. Sci, 19, 105-107.

Georgopoulos SD, Xirouchakis E, Martinez-Gonzalez B, Sgouras DN, Spiliadi C, Mentis AF, and Laoudi F. (2013) Clinical evaluation of a ten day regimen with Esomeprazole, Metronidazole, Amoxicil-lin, and Clarithromycin for the eradication of Helicobacter pylori in a high Clarithromycin resistance ar-ea. Helicobacter. 2013 Dec; 18(6):459-67.

Papadakos KS, Sougleri IS, Mentis AF, Hatziloukas E, Sgouras DN. (2013) Presence of Terminal EPIYA Phosphorylation Motifs in Helicobacter pylori CagA Contributes to IL-8 Secretion, Irrespective of the Number of Repeats. PLoS One 8:e56291.

Papadakos KS, Sougleri IS, Mentis AF, Sgouras DN. (2013) A Mutagenesis Method for the Addition and Deletion of Highly Repetitive DNA Regions: The Paradigm of EPIYA Motifs in the cagA Gene of Helicobacter pylori. Helicobacter; 18(3):229-41.


Mueller D, Tegtmeyer N, Brandt S, Yamaoka Y, De Poire E, Sgouras D, Wessler S, Torres J, Smolka A, Backert S. (2012) c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains. Journal of Clinical Inves-tigation 122:1553-1566.

Altman E, Chandan V, Harrison BA, Panayotopoulou EG, Roma-Giannikou E, Li J, Sgouras DN. (2012) Helicobacter pylori isolates from Greek children express type 2 and type 1 Lewis and alpha 1,6-glucan antigens in conjunction with a functional type IV secretion system. Journal of Medical Mi-crobiology 61:559- 566.

Boziki M, Grigoriadis N, Deretzi G, Lagoudaki R, Panayotopoulou E, Sgouras D, Mentis A, Tascos N, Kountouras J. (2012) Helicobacter pylori Immunomodulative Properties in a Mouse Model of Multiple Sclerosis. Immunogastroenterology 1: 34-39


Breurec S, Michel R, Seck A, Brisse S, Come D, Dieye FB, Garin B, Huerre M, Mbengue M, Fall C, Sgouras DN, Thiberge JM, Dia D, Raymond J. (2011) Clinical relevance of cagA and vacA gene pol-ymorphisms in Helicobacter pylori isolates from Senegalese patients. Clinical Microbiology and Infec-tion 18:153-159.

Breurec S, Guillard B, Hem S, Papadakos KS, Brisse S, Huerre M, Monchy D, Oung C, Sgouras DN, Tan TS, Thiberge J-M, Vong S, Raymond J, Linz B. (2011) Expansion of European vacA and cagA alleles to East-Asian Helicobacter pylori strains in Cambodia. Infection Genetics and Evolution 11:1899-1905.


Roma-Giannikou E, Roubani A, Sgouras DN, Panayiotou J, van-Vliet C, Polyzos A, Roka K, Daikos G. (2010) Endoscopic Tests for the Diagnosis of Helicobacter pylori Infection in Children: Validation of Rapid Urease Test. Helicobacter 15:227-232.

Panayotopoulou EG, Sgouras DN, Papadakos KS, Petraki K, Breurec S, Michopoulos S, Mantzaris G, Papatheodoridis G, Mentis A, Archimandritis A. (2010) CagA and VacA Polymorphisms Are Associat-ed with Distinct Pathological Features in Helicobacter pylori-Infected Adults with Peptic Ulcer and Non-Peptic Ulcer Disease. Journal of Clinical Microbiology 48:2237-2239.


Sgouras DN, Panayotopoulou EG, Papadakos K, Martinez-Gonzalez B, Roumbani A, Panayiotou J, vanVliet-Constantinidou C, Mentis AF, Roma-Giannikou E. (2009) CagA and VacA Polymorphisms Do Not Correlate with Severity of Histopathological Lesions in Helicobacter pylori-Infected Greek Children. Journal of Clinical Microbiology 47:2426-2434.

Maragkoudakis PA, Papadelli M, Georgalaki M, Panayotopoulou EG, Martinez-Gonzalez B, Mentis AF, Petraki K, Sgouras DN, Tsakalidou E. (2009) In vitro and in vivo safety evaluation of the bacteri-ocin producer Streptococcus macedonicus ACA-DC 198. International Journal of Food Microbiology 133:141-147.

Alam MZ, Haralambous C, Kuhls K, Gouzelou E, Sgouras D, Soteriadou K, Schnur L, Pratlong F, Schoenian G. (2009) The paraphyletic composition of Leishmania donovani zymodeme MON-37 re-vealed by multilocus microsatellite typing. Microbes and Infection 11:707-715.


Paraschos S, Magiatis P, Mitakou S, Petraki K, Kalliaropoulos A, Maragkoudakis P, Mentis A, Sgour-as D, Skaltsounis A-L. (2007) In vitro and in vivo activities of chios mastic gum extracts and constitu-ents against Helicobacter pylori. Antimicrobial Agents and Chemotherapy 51:551-559.

Panayotopoulou EG, Sgouras DN, Papadakos K, Kalliaropoulos A, Papatheodoridis G, Mentis AF, Ar-chimandritis AJ. (2007) Strategy to characterize the number and type of repeating EPIYA phosphory-lation motifs in the carboxyl terminus of CagA protein in Helicobacter pylori clinical isolates. Journal of Clinical Microbiology 45:488-495.


Sgouras DN, Panayotopoulou EG, Martinez-Gonzalez B, Petraki K, Michopoulos S, Mentis A. (2005) Lactobacillus johnsonii La1 attenuates Helicobacter pylori-associated gastritis and reduces levels of proinflammatory chemokines in C57BL/6 mice. Clinical and Diagnostic Laboratory Immunology 12:1378- 1386.


Sgouras D, Maragkoudakis P, Petraki K, Martinez-Gonzalez B, Eriotou E, Michopoulos S, Kalantzopoulos G, Tsakalidou E, Mentis A. (2004) In vitro and in vivo inhibition of Helicobacter pylori by Lactobacillus casei strain Shirota. Applied and Environmental Microbiology 70:518-526.

De Vuyst L, Makras L, Avonts L, Holo H, Yi Q, Servin A, Fayol-Messaoudi D, Berger C, Zoumpopou-lou G, Tsakalidou E, Sgouras D, Martinez-Gonzales B, Panayotopoulou E, Mentis A, Smarandache D, Savu L, Thonart P, Nes I. (2004) Antimicrobial potential of probiotic or potentially probiotic lactic acid bacteria, the first results of the International European Research Project PROPATH of the PROEU-HEALTH cluster. Microbial Ecology in Health and Disease 16:125-130. Δείκτης Απήχησης: 0.780, Αναφορές: 16


Hynes SO, Broutet N, Wadstrom T, Mikelsaar M, O'Toole PW, Telford J, Engstrand L, Kamiya S, Mentis AF, Moran AP. Phenotypic variation of Helicobacter pylori isolates from geographically distinct regions detected by lectin typing. J Clin Microbiol. 2002 Jan;40(1):227-32.


Kalpoutzakis E, Aligiannis N, Mentis A, Mitaku S, Charvala C. Composition of the essential oil of two Nepeta species and in vitro evaluation of their activity against Helicobacter pylori. Planta Medica, 2001:67,880-3.

Petridou Ε, Dalamaga M, Mentis A, Skalkidou A, Moustaki M, Karpathios T, Trichopoulos D, and the Childhood Haematologists-Oncologists Group. Evidence supporting the infectious aetiology of child-hood leukaemia: the role of low herd immunity. Cancer Causes Control Journal, 2001:12,645-52.

Magiatis P, Spanakis D, Mitaku S, Tsitsa E, Mentis A, Harvala C. Verbalactone, a new macrocyclic dimer lactone from the roots of Verbascum undulatum with antibacterial activity. Nat Prod, 2001:64, 1093-4.


Georgopoulos, S. Ladas, S Karatapanis, AF Mentis, Ch Spiliadi, V. Artikis, SA Raptis. Factors that may affect treatment outcome of triple Helicobacter pylori eradication therapy with omeprazole, amoxicillin, and clarithromycin. Dig Dis Sci, 2000;45:63-67.



Dionyssios Sgouras

Research Director

Beatriz Martinez- Gonzalez

Staff Res. Scientist

Ioannis Karayiannis

Post-graduate PhD Student

Eleftherios Kontizas

Post-graduate PhD Student

Evangelia Sotiropoulou

Post-graduate PhD Student

George Georgoulias

Post-graduate MSc Student

Eleni Petrou

Post-graduate MSc Student


Dr. Andreas Mentis

Research Director (2013-2022)


Ioanna Sougleri (PhD, alumnus since 2018)
Kostas Papadakos (PhD, alumnus since 2015)
Elissavet Kotsi (PhD, alumnus since 2014)
Effrosini Panayotopoulou(PhD, alumnus since 2013)
Maria Karapanou (MSc, alumnus since 2022)
Dionysia Stamiri (MSc, alumnus since 2022)
Elisavet Michailou (MSc, alumnus since 2020)
Vassilios Lygnos (MSc, alumnus since 2019)
Chrisoula Kartsiouka (MSc, alumnus since 2019)
Nikolaos Psarras (MSc, alumnus since 2019)
Andreas Mazis (MSc, alumnus since 2019)
Gesthimani Papadopoulou (MSc, alumnus since 2019)
Panagiotis Mimidis (MSc, alumnus since 2019)
Achilleas Eleftheriadis (MSc, alumnus since 2018)